The tiny proteins that can alert us to some of the most acute human disorders—traumatic brain injury (TBI), cancer, heart attack, and stroke—are freely circulating in our blood, urine, and other bodily fluids. But detecting these tiny “biomarkers” is problematic and costly. Biomarkers are not only tiny but very dilute. The most direct approach to...
Grow and eat your own vaccines?
UNIVERSITY OF CALIFORNIA – RIVERSIDE IMAGE: CHLOROPLASTS (MAGENTA) IN LEAVES EXPRESSING A GREEN FLUORESCENT PROTEIN. THE DNA ENCODING FOR THE PROTEIN WAS DELIVERED BY TARGETED NANOMATERIALS WITHOUT MECHANICAL AID BY APPLYING A DROPLET OF THE NANO-FORMULATION TO THE LEAF SURFACE. CREDIT: ISRAEL SANTANA/UCR The future of vaccines may look more like eating a salad than...
A novel malaria vaccine vector – target to the liver
KANAZAWA UNIVERSITY IMAGE: THE IVIS IMAGING RESULTS FOR THE LIVERS COLLECTED FROM MICE ON DAY 8 OR DAY 224 POST-ADMINISTRATION OF AAV-LUC SHOWED THAT SYSTEMIC ADMINISTRATION OF AAV8 INDUCED ~24–43 TIMES BETTER LIVER LUCIFERASE ENZYME ACTIVITY WHEN COMPARED WITH I.M. ADMINISTRATION. CREDIT: KANAZAWA UNIVERSITY Kanazawa, Japan – Malaria remains a deadly disease that affects people...
Researchers explore promising new stem cell treatment for MRSA superbug
ALPHAMED PRESS IMAGE: THE EQUINE EX VIVO SKIN BIOFILM EXPLANT MODEL WITH AN IMAGE OF SKIN EXPLANTS IN CULTURE (LEFT) AND BACTERIAL BIOFILMS STAINED WITH ALCIAN BLUE (UPPER RIGHT) AND AN ANTI-BACTERIAL ANTIBODY (LOWER RIGHT) TO SHOW THE PRESENCE OF BACTERIA IN THE SKIN BIOFILM EXPLANT MODEL. CREDIT: ALPHAMED PRESS Durham, NC – A study released...
Biologists identify new targets for cancer vaccines
MASSACHUSETTS INSTITUTE OF TECHNOLOGY CAMBRIDGE, MA — Over the past decade, scientists have been exploring vaccination as a way to help fight cancer. These experimental cancer vaccines are designed to stimulate the body’s own immune system to destroy a tumor, by injecting fragments of cancer proteins found on the tumor. So far, none of these...
Statins may be effective treatment for patients with ulcerative colitis
STANFORD MEDICINE There may be good news for the nearly 1 million people battling ulcerative colitis, a type of inflammatory bowel condition with no real cure: Statins, a commonly prescribed cholesterol-lowering drug, seem to be an effective, if unexpected, treatment for the condition, according to a new Stanford Medicine study. Currently, the only lines of defense against...
Research provides new insight into fundamental workings of the immune system in response to therapy to treat skin cancer
UNIVERSITY OF BIRMINGHAM New research led by the University of Birmingham suggests that skin cancer patients could have a better prognosis if their T cells send messages from five specific genes in their immune response to drugs given to treat the disease. The research, carried out in mice, cells in the laboratory, and using publicly available data...
Discovery of rapid-response signaling platform suggests new path for blocking allergic inflammation
CINCINNATI CHILDREN’S HOSPITAL MEDICAL CENTER IMAGE: ILLUSTRATION DETAILS THE MECHANISMS OF THE BODY’S ALLERGEN-SENSING SYSTEM. CREDIT: CINCINNATI CHILDREN’S New discoveries about a built-in rapid reaction system that triggers inflammatory responses when people are exposed to allergens, such as insects, mites, and fungi, also may hold the keys to helping more people manage their allergies in...
New study identifies likely cause of Alzheimer’s disease
by Curtin University Diagram of the brain of a person with Alzheimer’s Disease. Credit: Wikipedia/public domain. Ground-breaking new Curtin University-led research has discovered a likely cause of Alzheimer’s disease, in a significant finding that offers potential new prevention and treatment opportunities for Australia’s second-leading cause of death. The study, published in the prestigious PLOS Biology journal and tested...
Research reveals drug targets for memory enhancement
by University of Bristol Credit: Unsplash/CC0 Public Domain Bristol-led research has identified specific drug targets within the neural circuits that encode memories, paving the way for significant advances in the treatment of a broad spectrum of brain disorders. Loss of memory is a core feature of many neurological and psychiatric disorders including Alzheimer’s disease and schizophrenia. Current treatment...