by University of Virginia Credit: Pixabay/CC0 Public Domain Damaging DNA builds up in the eyes of patients with geographic atrophy, an untreatable, poorly understood form of age-related macular degeneration that causes blindness, new research from the University of Virginia School of Medicine reveals. Based on the discovery, the researchers think it may be possible to treat the disease with common...
New treatment uses reverse vaccination to teach immune system not to attack life-saving drugs
by Marcene Robinson, University at Buffalo Biophysical characteristics of lipid nanoparticles for immunotherapy. (a) Surface exposure of different PS species on the nanoparticles as detected by PSVue fluorescence signal. Changes in fluorescence intensity I/I0 were monitored as a function of total lipid concentration and fitted in GraphPad Prism using a single site-total binding model with nonlinear...
Scientists investigate how infection by SARS-CoV-2 can lead to kidney disorders
IMAGE: LOSS OF ACE2 LEADS TO AN IMBALANCE IN SYSTEMS THAT REGULATE ESSENTIAL METABOLIC FUNCTIONS, IMPAIRING BLOOD FILTRATION AND CAUSING KIDNEY INJURIES THAT CAN BECOME PERMANENT CREDIT: HOLLY FISCHER/HOLLY FISCHER/WIKIMEDIA COMMONS HTTPS://COMMONS.WIKIMEDIA.ORG/WIKI/FILE:KIDNEY_CROSS_SECTION.PNG A review article published in the journal Frontiers in Physiology by researchers affiliated with the Federal University of São Paulo (UNIFESP) in Brazil discusses the mechanisms whereby SARS-CoV-2...
What are ideal blood sugar levels for preventing repeat strokes, heart attacks?
MINNEAPOLIS – Blood sugar control has always been important for people with diabetes when it comes to preventing a stroke. But a new study finds for people with diabetes who have a stroke, there may be an ideal target blood sugar range to lower the risk of different types of vascular diseases like a stroke or...
Aging memories may not be ‘worse,’ just ‘different’
by Brandie Jefferson, Washington University in St. Louis “Older adults might be representing events in different ways, and transitions might be picked up differently than, say, a 20-year-old,” said Zachariah Reagh, assistant professor of psychological and brain sciences in Arts & Sciences. Reagh looked at fMRI images to study memory differences in different age groups. Credit:...
Manic episodes in bipolar disorder linked to abnormal brain changes
by Karolinska Institutet Figure 1. Effect sizes (Cohen’s d; top) and significance of group differences (p-value; bottom) between BD patients and HC mapped into brain space. Cortical thickness findings (left) and surface area findings (right) are shown. The Figure displays the overall pattern in the uncorrected raw results. See Figure 3 for findings after multiple comparisons...
A Gene-Editing Experiment Let These Patients With Vision Loss See Color Again
ROB STEIN Carlene Knight, who has a congenital eye disorder, volunteered to let doctors edit the genes in her retina using CRISPR.Franny White/OHSU Carlene Knight’s vision was so bad that she couldn’t even maneuver around the call center where she works using her cane. “I was bumping into the cubicles and really scaring people that...
Radiation to the heart corrects arrhythmia by reactivating younger state
By Michael Irving September 28, 2021 Scientists have found that radiation therapy could be a less invasive treatment for arrhythmia Tolokonov/Depositphotos Scientists at the Washington University School of Medicine have made an intriguing discovery that could see radiation therapy become a less invasive treatment for heart arrhythmia. The technique seems to activate the heart cells...
New tests for colon, prostate cancer show promise
by Dennis Thompson A pair of experimental tests could help doctors detect colon or prostate cancer with just a sample of blood or saliva. One test examines a person’s blood for four biomarkers linked to inflammation. In a small study, it outperformed the fecal blood test now used in colon cancer screening, said lead researcher Dr. Mona Eldeeb,...
Intense workouts shortly before bed found to impact sleep quality
By Nick Lavars September 28, 2021 A new study suggests that avoiding high-intensity workouts within two hours of bedtime is best for a sound night’s sleepchoreograph/Depositphotos It is well known that a physically active day can make for a better night’s rest, and a new study has delved into how the timing of our workouts...