A quick online search for ways to improve our mental health will often come up with a myriad of different results. However, one of the most common suggestions put forward as a step to achieving wellness – and preventing future issues – is doing some physical exercise, whether it be a walk or playing a...
Medicine that treats gout could also battle COVID-19
by University of Georgia Ralph Tripp, GRA Eminent Scholar of Vaccine and Therapeutic Studies at the University of Georgia. Credit: UGA As COVID-19 cases continue to skyrocket across the U.S. and the world, few options are available for treating patients infected with the SARS-CoV-2. But new research from the University of Georgia offers hope for a viable therapeutic...
A T-cell power-up for tumor treatments
by University of Southern California Credit: DOI: 10.1089/hum.2021.050 Cancer is the second leading cause of death in the United States. But in recent years, a revolutionary therapy has brought new hope in the fight against the disease that takes the lives of nearly 600,000 Americans each year. Chimeric Antigen Receptor (CAR) T-cell therapy is a highly...
Drugs that mimic effects of cigarette smoke reduce SARS-CoV-2’s ability to enter cells
by Hiroshima University A team of Japanese scientists demonstrates that treatment with AHR agonists decreases expression of ACE2 via AHR activation, resulting in suppression of COVID-19. Credit: DBCLS TogoTV / CC-BY-4.0 Researchers have identified a potential reason why lower numbers of COVID cases have appeared amongst smokers compared to non-smokers, even as other reports suggest smoking increases...
Association between standing and insulin sensitivity
by University of Turku Fig. 1. Dose-response association between standing time and insulin sensitivity. Insulin sensitivity presented as a) M-value and b) HOMA-IR stratified by tertiles of accelerometer-measured standing time (h/day; means [SD]) in sedentary adults with metabolic syndrome (n = 64). HOMA-IR = homeostatic model assessment of insulin resistance. ** = p < 0.01, *** = p < 0.001. Credit: DOI: 10.1016/j.jsams.2021.08.009 Insulin is a key hormone...
Omics data suggests larger effect of smoking on body mass index than previously thought
by Public Library of Science Credit: monstreh, Pixabay, CC0 (creativecommons.org/publicdomain/zero/1.0/) Smoking-related DNA methylation patterns explain around a fifth of the variation in body mass index (BMI) between individuals, according to a study publishing September 9th in the open-access journal PLOS Genetics, led by Carmen Amador at the University of Edinburgh. Amador and colleagues analyzed genomic sequence data from over...
Vitamin D and lumisterol emerge as cheap and easily accessible potential treatments for COVID-19
by American Physiological Society Credit: Pixabay/CC0 Public Domain Promising new data from a recent study indicates that active forms of vitamin D can inhibit the replication and expansion of COVID-19. The study’s findings also suggest lumisterol, produced by a chemical reaction in the body using light, works to block COVID-19. Vitamin D and lumisterol metabolites were...
Brain molecule helps ‘wake up’ cells that could help tackle MS and similar diseases, study shows
by University of Alberta Faculty of Medicine & Dentistry Credit: Pixabay/CC0 Public Domain An immunological molecule called fractalkine can boost the production of brain cells that produce myelin, a key factor in diseases such as multiple sclerosis, according to recent research from the University of Alberta. Myelin is an insulating layer around nerves that is gradually worn away...
Mu SARS-CoV-2 variant highly resistant to neutralization by convalescent and vaccinated sera
Researchers in Japan have warned that the Mu (B.1.621) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – appears to be highly resistant to neutralization by sera from convalescent or vaccinated individuals. The B.1.621 variant, first isolated in Colombia in January this year (2021), was classified...
Reversal of the biological hallmarks responsible for development of Alzheimer’s disease and dementia using unique hyperbaric oxygen therapy protocol
IMAGE: STUDY RESULTS SHOW ELEVATED BLOOD FLOW AND IMPROVED OXYGENATION IN THE BRAIN OF PATIENTS SUFFERING FROM COGNITIVE IMPAIRMENT CREDIT: TEL AVIV UNIVERSITY (TAKEN FROM THE ARTICLE). Scientific Breakthrough: A team of investigators from Tel Aviv University has succeeded in restoring brain trauma by hyperbaric oxygen therapy (HBOT). This is the first time in the...