By Emily Henderson, B.Sc. Sep 29 2021 Researchers at the University of East Anglia and James Paget University Hospital are launching a new project to see whether Vitamin A could help people regain their sense of smell after viral infections including COVID-19. We also spoke exclusively to Professor Carl Philpott who is leading the study to find...
As tumors grow within an organ, they also release cells that enter the bloodstream. These cells can travel to other organs, seeding new tumors called metastases. MIT engineers have now developed a technique that, for the first time, allows them to measure the generation rate of these circulating tumor cells (CTCs) in mice. Their approach,...
It’s as true in the realm of infectious disease as combat. And the University of Nebraska–Lincoln’s Limei Zhang subscribes to the maxim that best encapsulates it. “In order to fight your enemies, you have to know how your enemies survive and attack you,” said Zhang, associate professor of biochemistry. “That’s the fundamental question we are looking at.”...
The processes of autophagy act to remove damaged molecular machinery and structures in the cell. Autophagy becomes dysfunctional with age, however. This is likely downstream of underlying causes of aging that cause changes in gene expression that degrade the function of autophagic processes in one way or another. For example mitophagy, the clearance of damaged mitochondria by autophagy, is indirectly negatively...
SEPTEMBER 28TH, 2021 CONN HASTINGS MATERIALS, MEDICINE, SURGERY A team of scientists at Purdue University created a microneedle patch that can deliver oxygen and bactericidal agents to chronic wounds. The bacterial biofilms that form over non-healing wounds, such as foot ulcers, are a formidable barrier to successful treatment. Such wounds are typically hypoxic and the bacteria within...
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO IMAGE: LOSS OF ACE2 LEADS TO AN IMBALANCE IN SYSTEMS THAT REGULATE ESSENTIAL METABOLIC FUNCTIONS, IMPAIRING BLOOD FILTRATION AND CAUSING KIDNEY INJURIES THAT CAN BECOME PERMANENT CREDIT: HOLLY FISCHER/HOLLY FISCHER/WIKIMEDIA COMMONS HTTPS://COMMONS.WIKIMEDIA.ORG/WIKI/FILE:KIDNEY_CROSS_SECTION.PNG A review article published in the journal Frontiers in Physiology by researchers affiliated with the Federal University of...
BOSTON UNIVERSITY SCHOOL OF MEDICINE The APOE gene—coding for a protein involved in lipid transport and implicated in the clearance of amyloid-beta, one of the proteins that builds up in the brain in Alzheimer’s disease—exists in three allelic forms: E4, E3, and E2. Researchers have strong evidence that the presence of E4 constitutes a risk factor for...
KAROLINSKA INSTITUTET Researchers at Karolinska Institutet in Sweden have identified a protein that improves muscular metabolism, motor coordination, and exercise performance in mice. The findings, published in Cell Metabolism, could be of therapeutic value for patients with muscle and neurological diseases, such as ALS. Muscle health is a major determinant of overall health and the...
by University of Nevada, Las Vegas Credit: Pixabay/CC0 Public Domain A team of UNLV neuroscientists has strengthened the link between Type II diabetes and Alzheimer’s disease. In a study published in the September issue of the journal Communications Biology, researchers show that chronic hyperglycemia impairs working memory performance and alters fundamental aspects of working memory networks. “Diabetes is a...
by Arizona State University A child decides whether Maxi will look for the chocolate bar in the blue, red or green box. When there are two possible locations of the chocolate bar, children can answer correctly without understanding how other people think. When there are more than two locations, children must understand how Maxi can have...
