Month: <span>September 2021</span>

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Study shows how a racing heart may alter decision-making brain circuits
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Study shows how a racing heart may alter decision-making brain circuits

by  The Mount Sinai Hospital Credit: Pixabay/CC0 Public Domain Anxiety, addiction, and other psychiatric disorders are often characterized by intense states of what scientists call arousal: The heart races, blood pressure readings rise, breaths shorten, and “bad” decisions are made. In an effort to understand how these states influence the brain’s decision-making processes, scientists at the...

Glowing antibacterial bandage sheds light on infected wounds
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Glowing antibacterial bandage sheds light on infected wounds

If the bandage glows under UV light, it means that an infection is presentRMIT UniversityVIEW 3 IMAGES Bandaged wounds need to be checked for infection, yet removing the bandage to check the wound can delay its healing. Australian scientists may have a fix for this paradox, in the form of a dressing that glows if...

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Higher intake of specific nutrients linked to lower brain iron and better cognition in older adults

Reviewed by Emily Henderson, B.Sc.Aug 26 2021 Research conducted at the University of Kentucky College of Medicine suggests that higher intake of specific nutrients is associated with lower brain iron concentration and better cognitive performance in older adults. The study was recently published in the Neurobiology of Aging and highlights the important balance of non-heme iron for...

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Lipid-lowering drug TriCor dramatically cuts treatment time for severe COVID-19 patients

Reviewed by Emily Henderson, B.Sc.Aug 23 2021 The SARS-CoV-2 virus has infected over 165 million people worldwide causing nearly 3.5 million deaths. Recent vaccination efforts have been hindered by multiple coronavirus variants that challenge current vaccines. While infection generally produces a mild disease, in some patients it can develop into a severe inflammatory COVID-19 requiring medical...

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1 ANTIBODY NEUTRALIZES A BUNCH OF COVID VIRUS VARIANTS

The virus today is not the same as the one that first sickened people back in December 2019. Many of the variants circulating now are partially resistant to some of the antibody-based therapeutics that were developed based on the original virus. As the pandemic continues, more variants inevitably will arise, and the problem of resistance...

Neurons in visual cortex of the brain ‘drift’ over time
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Neurons in visual cortex of the brain ‘drift’ over time

Although other studies have documented “representational drift” in neurons in the parts of the brain associated with odor and spatial memory, this result is surprising because neural activity in the primary visual cortex is thought to be relatively stable. The study published in Nature Communications was led by Ji Xia, a recent PhD graduate of the laboratory of Ralf...

Genome “archipelago” as new model of how genomic information influences development and disease
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Genome “archipelago” as new model of how genomic information influences development and disease

 A University at Buffalo team has developed a new model of how information in the genome is organized, called the novel genome archipelago model (GAM). The model provides new insights into how a multitude of interactions among genes may affect normal development as well as mutations that lead to cancer and other diseases. “GAM offers...

Synthetic biology enables microbes to build muscle
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Synthetic biology enables microbes to build muscle

IMAGE: RESEARCHERS AT THE MCKELVEY SCHOOL OF ENGINEERING AT WASHINGTON UNIVERSITY IN ST. LOUIS HAVE DEVELOPED A SYNTHETIC CHEMISTRY APPROACH TO POLYMERIZE PROTEINS INSIDE OF ENGINEERED MICROBES. THIS ENABLED THE MICROBES TO PRODUCE THE HIGH MOLECULAR WEIGHT MUSCLE PROTEIN, TITIN, WHICH WAS THEN SPUN INTO FIBERS. IN THE FUTURE, SUCH MATERIAL COULD BE USED FOR...

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Monoclonal antibody treatment combo reduces hospitalization among high-risk patients with COVID-19

ROCHESTER, Minn. ― In an observational study, Mayo Clinic researchers report that the combination of casirivimab and imdevimab ― two monoclonal antibody treatments under Food and Drug Administration emergency use authorization ― keep high-risk patients out of the hospital when infected with mild to moderate COVID-19. The findings appear in The Lancet’s EClinicalMedicine. Nearly 1,400 Mayo Clinic patients...

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Unsupervised AI breaks new ground by predicting the progression of COVID-19 and survival of patients directly from their chest CT images

BOSTON – Fast and accurate clinical assessment of the disease progression and mortality is vital for the management of COVID-19 patients. Although several predictors have been proposed, they have been limited to subjective assessment, semi-automated schemes, or supervised deep learning approaches. Such predictors are subjective or require laborious annotation of training cases. In a multi-center study...