by Diane Toroian Keaggy, Washington University in St. Louis Credit: CC0 Public Domain Want good grades? Get a good semester’s sleep. But good sleep, it turns out, is not just about quantity. It’s also about consistency. Research from Tim Bono, lecturer in psychological and brain sciences in Arts & Sciences at Washington University in St. Louis, found...
by American Physiological Society Figure 1. A representative image showing a 20-s polysomnography (PSG) sleep tracing including electrooculography (EOG), electroencephalography (EEG; F3, C3, and O1 leads), chin electromyography (EMG), electrocardiogram (ECG), and respiration (Resp). The light gray box outlines an exemplary cortical arousal as marked by an abrupt shift in the EEG frequency. Credit: DOI:...
BAYLOR COLLEGE OF MEDICINE A multi-institution team of researchers led by scientists at Baylor College of Medicine has discovered a genetic signature that can identify drivers of poor outcomes in advanced estrogen-receptor positive (ER+) breast cancer, which could one day lead to personalized treatment for patients. The 24-gene signature detects the presence of mutations and translocations in...
NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY Osteoarthritis is the leading cause of pain and disability worldwide. There is no cure, only pain relief. Patients’ joints become inflamed, and they feel creaky and stiff in the morning. Some people use painkillers and exercise as treatment. Others have to resort to surgery and prostheses. About 300 million people...
UNIVERSITY OF ALABAMA AT BIRMINGHAM IMAGE: BEN LARIMER CREDIT: UAB BIRMINGHAM, Ala. – Immunotherapy using checkpoint inhibitors can work well to treat cancer, but only a minority of patients respond to therapy. Researchers at the University of Alabama at Birmingham have now shown — in preclinical experiments — how to identify non-responding tumors and improve their response to...
UNIVERSITY OF LEICESTER A medicine licensed to treat psoriasis worsened symptoms in patients with severe asthma, according to trial results published today in the New England Journal of Medicine. The study, which was led by researchers at the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre – a partnership between Leicester’s Hospitals, the University...
UT SOUTHWESTERN MEDICAL CENTER IMAGE: JOACHIM HERZ, M.D. CREDIT: UT SOUTHWESTERN MEDICAL CENTER A study by UT Southwestern researchers finds that changing the biochemistry of parts of brain cells abolished the formation of amyloid beta plaques in a mouse model of Alzheimer’s disease. The finding, published in eLife, might eventually lead to treatments that prevent the memory-robbing...
VANDERBILT UNIVERSITY IMAGE: PANCREATIC ACINAR CELLS FORM A HETEROGENEOUS POPULATION OF NEW CELL TYPES IN RESPONSE TO INJURY WITH THE POTENTIAL TO LIMIT OR DRIVE DISEASE. ACINAR-DERIVED CLONES LABELED IN RED AND GREEN. CREDIT: DELGIORNO, ET. AL. The Idea Pioneering research from scientists at the Vanderbilt University School of Medicine Basic Sciences and the Salk...
by Brigham and Women’s Hospital Credit: CC0 Public Domain At the earliest stages of human embryonic development, a small collection of cells known as human embryonic stem cells (hESCs) orchestrates growth and differentiation, eventually giving rise to highly specialized human tissues. As pluripotent cells—progenitors of every type of cell type in the body—hESCs are of central...
by University of Illinois at Chicago Structural visualizations reveal that iboxamycin displaces the methylated nucleotide and binds in deep pocket of the ribosome. Credit: Polikanov, et al. A new study published in Nature reports on a new antibiotic that binds to the ribosome of bacterial cells and stops drug-resistant pathogens from making mice sick. Co-authored by researchers...
