by The Mount Sinai Hospital Level of association of more than 7.5 million common genetic variants with suicide attempt, before and after adjusting for psychiatric disorders. Genetic variants above the gray line pass the statistical significance level. Credit: Niamh Mullins, PhD, Assistant Professor of Psychiatry, Icahn School of Medicine at Mount Sinai In the largest genetic...
Diabetes drug dapagliflozin may benefit patients with heart failure
by Melissa Rohman, Northwestern University Effects of dapagliflozin on selected secondary endpoints and in supportive responder analysis. a–c, Effects of dapagliflozin on selected secondary endpoints and in supportive responder analysis. Effects of dapagliflozin versus placebo at 12 weeks on 6MWT distance (a), KCCQ-CS responder analysis (b) and KCCQ-OS (c). Data are presented as mean values with 95%...
Study shows certain brain waves aren’t just background noise
by Laurel Hamers, University of Oregon Credit: CC0 Public Domain Even when at rest, the brain is never truly quiet. New research in mice sheds light on the seemingly random brain signals that hum in the background of brains. These signals might help the brain switch between states of inattention or disengagement and states of optimal performance, UO...
Novel system invented for preventing cardiovascular diseases, non-invasively
by Zhao Weiwei, Hefei Institutes of Physical Science, Chinese Academy of Sciences Credit: Hefei Institutes of Physical Science, Chinese Academy of Sciences Cardiovascular diseases (CVDs) are the leading cause of death globally. Monitoring of lipid in patients with coronary heart disease (CHD) is important for decreasing the incidence of cardiovascular events. The traditional indicator, Low-density...
Heart repair and regeneration after a heart attack: A review
by Jeff Hansen, University of Alabama at Birmingham Credit: Pixabay/CC0 Public Domain Twenty years ago, clinicians first attempted to regenerate a failing human heart by injecting muscle myoblasts into the heart during a bypass operation. Despite high initial hopes and multiple experimental and clinical studies since then, outcomes have been neutral or marginally positive for...
Research team identifies new rare disease affecting hematopoiesis and immunity
by St. Anna Children’s Cancer Research Institute Credit: CC0 Public Domain The immune system is one of the most complex and fascinating networks in the human body. Comprised of cellular and humoral components, it not only protects us against external intruders such as viruses or bacteria, but also plays a fundamental role in detecting aberrant...
An overview of the effectiveness of anti-aging diets
by Bob Yirka, Medical Xpress Credit: CC0 Public Domain A small team of researchers from the University of Washington and one with the Pennington Biomedical Research Center, has conducted a review of research conducted regarding the effectiveness of anti-aging diets and has found little to suggest they work. In their paper published in the journal Science,...
New scaffold design improves growth of regenerating neurons
by Okinawa Institute of Science and Technology The scaffold, imaged using an electron microscope, is structurally designed to help guide regenerating neurons. Image A: scale bar = 100 µm. Image B: scalebar = 1 µm. Credit: Okinawa Institute of Science and Technology Across the world, several million people every year suffer from spinal cord injury....
Wireless network controls brain circuits remotely via the internet
by The Korea Advanced Institute of Science and Technology (KAIST) Credit: Pixabay/CC0 Public Domain A new study shows that researchers can remotely control the brain circuits of numerous animals simultaneously and independently through the internet. The scientists believe this newly developed technology can speed up brain research and various neuroscience studies to uncover basic brain...
Gut microbiome genetically edited in live mice for the first time
By Michael Irving November 28, 2021 Bacteriophages attack a bacterium, which according to a new study could be useful for manipulating the gut microbiomeiLexx/Depositphotos Scientists at the University of California San Francisco (UCSF) have successfully edited the genome of bacteria in the gut microbiome of living mice, for the first time. Bacteria-hunting viruses are loaded...