by Heidelberg University Cultured neurons from the striatum of mice. Credit: Thomas Lissek / Hilmar Bading A molecular switch influences addiction behavior and determines how strong the response to addictive drugs is. A research team at Heidelberg University and the Sorbonne University in Paris (France) made the discovery in mice treated with cocaine. The researchers...
Virtually guided exposure therapy improves outcomes in patients with post-traumatic stress disorder: preliminary study
by Kimberly McGhee, Medical University of South Carolina The components of the Bio Ware kit. Photograph provided by Periscope. Credit: Zeriscope. Virtually guided prolonged exposure therapy reduced post-traumatic stress disorder (PTSD) symptoms more effectively than prolonged exposure alone in a pilot study of 40 civilians and veterans. The study was conducted at the Medical University...
Chromatin architecture reveals vulnerabilities to neurodegenerative movement disorders
by St. Jude Children’s Research Hospital Credit: CC0 Public Domain A genomic architectural discovery made deep inside neurons of the brain’s movement control center reveals how DNA packaging may contribute to neurodegenerative diseases. St. Jude Children’s Research Hospital scientists led the study, which appears today in Science Advances. The research focused on inherited pediatric neurodegenerative movement...
Cannabis cuts seizures by 86 percent in epileptic children
By Rich Haridy December 14, 2021 A series of 10 case reports indicate whole plant cannabis products could help reduce seizure frequency in children with severe epilepsyTPOphoto/Depositphotos A small UK study has found epileptic children treated with whole plant medicinal cannabis products displayed an 86 percent average reduction in seizure frequency. The researchers behind this...
BrainGlobe; An Open-Source Platform for Neuroscientists
Interview conducted by Emily Henderson, B.Sc.Dec 15 2021 Thought LeadersDr. Adam Tyson Professor Troy MargrieBrainGlobe An interview with Professor Troy Margrie, Associate Director of the Sainsbury Wellcome Centre, and Dr. Adam Tyson, former member of the Margrie lab and now the Scientific Software Lead at the Institute of Cancer Research. Please could you introduce yourself and...
CERTAIN HAIR PRODUCTS MAY ALTER HORMONES IN PREGNANCY
Personal care and beauty products contain several ingredients that often include a wide range of endocrine-disrupting chemicals like phthalates, parabens, phenols, and toxic metals. These chemicals interact with hormone systems, influencing synthesis, regulation, transport, metabolism, and hormone reception, which are all especially vulnerable during pregnancy. A new study in the journal Environmental Research examines the association...
Modulation of the Aged Gut Microbiome to Benefit Health is a Field in its Infancy
Research of the past decade makes it clear that it is plausible and possible to alter the aged gut microbiome in ways that will reduce chronic inflammation and improve long-term health. This goal has been achieved in animal models via a range of different means, including flagellin immunization and fecal microbiota transplantation. In short-lived species,...
NIH researchers identify potential AMD drugs with stem-cell based research tool
NIH/NATIONAL EYE INSTITUTE IMAGE: A 3D VIEW OF COMPLEMENT-ACTIVATED RPE CELLS (GREEN – CYTOSKELETON, BLUE – NUCLEUS) WITH DRUSEN/APOE (RED) DEPOSITS. CREDIT: RUCHI SHARMA AND DAVIDE ORTOLAN (NEI) Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment...
New study reveals how epithelial cells in the body naturally eliminate “precancerous” ones
WASEDA UNIVERSITY IMAGE: WASEDA UNIVERSITY RESEARCHERS IDENTIFY THE UNDERLYING MECHANISM BEHIND THE EXTRUSION OF PRECANCEROUS CELLS BY EPITHELIAL CELLS, A MECHANISM THAT PREVENTS THE FORMATION OF CANCEROUS LESIONS. CREDIT: WASEDA UNIVERSITY In addition to its immune surveillance system, recent reports have shown that the human body has defense mechanisms run by non-immune epithelial cells. Epithelial...
A potential protector against a mild heart attack’s aftereffects on metabolism
OHIO STATE UNIVERSITY COLUMBUS, Ohio – A new study in mice shows transplanted brown fat can reduce type 2 diabetes risk factors after a heart attack, an encouraging finding for scientists who hope to apply the so-called “good” fat’s beneficial properties to drugs that can help prevent health problems. In the study, transplanting brown fat...