Month: <span>December 2021</span>

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Are scientists homing in on a cure for Parkinson’s disease?
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Are scientists homing in on a cure for Parkinson’s disease?

by University of Bath Dr. Richard Meade. Credit: University of Bath A molecule that shows promise in preventing Parkinson’s disease has been refined by scientists at the University of Bath in the UK, and has the potential to be developed into a drug to treat the deadly neurodegenerative disease. Professor Jody Mason, who led the...

Half of top cancer studies fail high-profile reproducibility effort
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Half of top cancer studies fail high-profile reproducibility effort

Asher Mullard Vague experimental protocols was one barrier to replication that researchers encountered. Credit: Patrick Hertzog/AFP/Getty A US$2-million, 8-year attempt to replicate influential preclinical cancer research papers has released its final — and disquieting — results. Fewer than half of the experiments assessed stood up to scrutiny, reports the Reproducibility Project: Cancer Biology (RPCB) team...

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Upadacitinib in moderate to severe atopic dermatitis: high doses produce added benefit for adults

INSTITUTE FOR QUALITY AND EFFICIENCY IN HEALTH CARE Upadacinib is a new drug for the treatment of adults and adolescents aged 12 years and older with moderate to severe atopic dermatitis who are candidates for systemic therapy. In an early benefit assessment, the German Institute for Quality and Efficiency in Health Care (IQWiG) has now...

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New consensus care guideline will significantly improve quality of life for adults with Duchenne muscular dystrophy

IOS PRESS Amsterdam, December 9, 2021 – Many more adults with Duchenne muscular dystrophy (DMD) are living longer thanks to improvements in treatment, however international standards of care have not yet fully addressed the complex needs of these patients. The Adult North Star Network (ANSI) has developed a set of consensus-based recommendations designed to significantly...

Intersocietal position statement addresses confusion over ultrasound disinfection practices
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Intersocietal position statement addresses confusion over ultrasound disinfection practices

DOWLING & DENNIS PR VIDEO: THE VIDEO DEMONSTRATES AN ULTRASOUND-GUIDED PERIPHERAL IV INSERTION USING A PROPRIETARY BARRIER AND SECUREMENT DRESSING THAT REDUCES CONTAMINATION RISKS BY PREVENTING THE TRANSDUCER AND ULTRASOUND COUPLING GEL FROM COMING INTO CONTACT WITH THE NEEDLE INSERTION SITE. CREDIT: NANCY MOUREAU, RN, PHD Laurel, MD, December 9, 2021—Cleaning and low-level disinfection (LLD)...

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Breathlessness in patients with long COVID may signal heart problems

EUROPEAN SOCIETY OF CARDIOLOGY Sophia-Antipolis, 9 December 2021:A small study has suggested that COVID-19 patients who continue to be short of breath during physical activity one year after recovering from the infection may have suffered heart damage. The research is presented today at EuroEcho 2021, a scientific congress of the European Society of Cardiology (ESC).1...

Concerning rates of clarithromycin prescribing for H. pylori, despite increasing antibiotic resistance, uncovered in new Digestive Diseases & Sciences publication
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Concerning rates of clarithromycin prescribing for H. pylori, despite increasing antibiotic resistance, uncovered in new Digestive Diseases & Sciences publication

REDHILL BIOPHARMA IMAGE: REDHILL BIOPHARMA CREDIT: REDHILL BIOPHARMA RALEIGH, N.C. and TEL-AVIV, Israel, December 9, 2021, RedHill Biopharma Ltd.(Nasdaq: RDHL) (“RedHill” or the “Company”), a specialty biopharmaceutical company, today announced the publication in the journal Digestive Diseases and Sciences of a new study entitled “Pitfalls of Physician-Directed Treatment of Helicobacter pylori: Results from Two Phase...

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Talk between immune cells could lead to new cancer vaccine

YALE UNIVERSITY In the past decade, immunotherapy has helped save the lives of many cancer patients, many with lung cancer, who might have otherwise faced almost certain death sentences. However, only about 20% of patients who received immune therapies — designed to enhance or override natural limitations on immune system response — saw sustained benefits...

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Researchers identify brain signals associated with OCD symptoms, paving way for adaptive treatment

BROWN UNIVERSITY PROVIDENCE, R.I. [Brown University] — In an effort to improve treatment for obsessive compulsive disorder, a team of researchers has for the first time recorded electrical signals in the human brain associated with ebbs and flows in OCD symptoms over an extended period in their homes as they went about daily living. The research...

Tau and PQBP1: Protein interaction induces inflammation in the brain
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Tau and PQBP1: Protein interaction induces inflammation in the brain

by Tokyo Medical and Dental University  PQBP1 functions in brain microglia, which corresponds to dendritic cells or a part of macrophage regulating innate immune system, as an intracellular receptor for HIV cDNA and Tau proteins similarly. Credit: Department of Neuropathology, TMDU Just as a home security system can alert a homeowner to the presence of...