by Amanda Ferguson, University of Toronto Metformin 500mg tablets. Credit: public domain A widely used and inexpensive type 2 diabetes drug, once hoped to hold enormous promise in treating breast cancer, does not prevent or stop the spread of the most common forms of the disease, according to new research. The study, which has yet...
by Will Doss, Northwestern University Long-chain lipids (green) accumulate in the lysosomes (red) of disease cultures (right) but not in healthy cells (left). Credit: Northwestern University Whether or not someone develops Parkinson’s disease may be a game of nanometers. A recent study has demonstrated that chains of fatty acids in the lysosome just one-half nanometer...
DECEMBER 6TH, 2021 CONN HASTINGS ENT, MATERIALS, ONCOLOGY, SURGERY Researchers at McGill University developed a tough hydrogel that can resist mechanical forces found in the body. However, the material still provides a friendly environment for encapsulated cells to grow and enables the deep perfusion of blood and other tissue fluids. The injectable biomaterial may be useful...
by Bob Yirka, Medical Xpress Fig. 1: Characterisation of the capacity of GSE to eliminate senescent cells. a, Quantification of senescent PSC27 cell survival by SA-β-Gal positivity. GSE was applied to the medium at increasing concentrations. CTRL, control (proliferating) cells; SEN, senescent cells; NS, not significant. P values were calculated by one-way ANOVA with Tukey’s...
by Kyoto University A new study led by ASHBi Professor Motoko Yanagita finds the suppression of two molecules, CD153 and CD30, expressed on immune cells mitigates the progression of kidney disease. Credit: Kyoto University Despite nearly two million people dying of acute kidney injury every year, and tens of millions more needing treatment, no effective...
by Lauren Baggett, University of Georgia Credit: CC0 Public Domain Each day, clinicians and scientists are learning more about the acute and long-term health effects of COVID-19 on the body. A new study from the University of Georgia explores the potential impact of the virus on male fertility. The article, published recently in Nature Reviews Urology, reviews...
Researchers have in the past proposed links between oral bacteria and chronic inflammation, particularly in the heart and brain, proposing that bacterial toxins and bacteria themselves enter the bloodstream via damaged gums. This undoubtedly happens, but supporting data is mixed when it comes to the question of whether or not this has a meaningful effect size in comparison to...
by Ryan O’byrne, University of Alberta Faculty of Medicine & Dentistry Credit: CC0 Public Domain A team of University of Alberta researchers focused on aging Albertans has found that urinary incontinence could be a contributing factor in falls among older adults. In a study published in the journal PLOS ONE, the researchers showed for the first...
by Massachusetts General Hospital Credit: Pixabay/CC0 Public Domain Our internal 24-hour circadian clock regulates many aspects of physiology, including the response to infectious disease and vaccination. A new study published in the Journal of Biological Rhythms demonstrates that antibody levels are higher when people receive the SARS-CoV-2 vaccine in the afternoon versus the morning. “Our observational study...
(HealthDay)—Genetic testing can help guide management and treatment of unexplained epilepsy in children, new research suggests. “A genetic diagnosis impacted medical management for nearly three out of four children in our study,” said study author Dr. Isabel Haviland. She’s a postdoctoral research fellow in neurology/neurobiology at Boston Children’s Hospital and Harvard Medical School. In the study, Haviland’s...
