IMAGE: SCHEMATIC ILLUSTRATION OF THE NEW MOF ANTIBODY CRYSTALS AND THEIR ABILITY TO SPECIFICALLY SEEK OUT CANCER CELLS TO DETECT THEM AND DELIVER HIGHLY POTENT DRUGS WITH UNPRECEDENTED PRECISION. CREDIT: DR FRANCESCO CARRARO AND PROF PAOLO FALCARO (CO-FIRST AND CO-SENIOR AUTHOR ON THE ADVANCED MATERIALS PAPER) It sounds like the stuff of science fiction: a...
Targeted nanomedicine reduces vascular lesions, could help prevent stenosis
by University of Chicago Credit: CC0 Public Domain Vascular diseases like atherosclerosis can lead to serious complications, like heart attack or stroke. But many treatments for these diseases target systemic risk factors, such as reducing blood pressure and cholesterol, rather than repairing damaged blood vessels themselves. A new targeted nanomedicine treatment developed at the University of...
Scientists find first in human evidence of how memories form
by UT Southwestern Medical Center Credit: CC0 Public Domain In a discovery that could one day benefit people suffering from traumatic brain injury, Alzheimer’s disease, and schizophrenia, UT Southwestern researchers have identified the characteristics of more than 100 memory-sensitive neurons that play a central role in how memories are recalled in the brain. Bradley Lega, M.D.,...
Self-administered cognition test predicts early signs of dementia sooner
by Ohio State University Medical Center Dr. Douglas Scharre reviews the results of a patient’s cognitive test at The Ohio State University Wexner Medical Center. A new study finds the SAGE test he developed accurately identifies early signs of dementia at least six months earlier than standard testing, allowing treatment to start sooner. Credit: The Ohio...
US drug prices are costing us more than we think
by Neil Schoenherr, Washington University School of Medicine in St. Louis Credit: Pixabay/CC0 Public Domain Aduhelm, the first new Alzheimer’s drug in 18 years, could easily become the best-selling drug in Medicare, despite its potential massive cost and tremendous uncertainty about whether the drug even works, says Rachel Sachs, the Treiman Professor of Law and nationally...
Scientists seek to shift treatment of kidney damage caused by cancer drug
by Jane E. Dee, Yale University Credit: Unsplash/CC0 Public Domain In a new paper accepted for publication in the Journal of the American Society of Nephrology, researchers at Yale School of Medicine share findings that indicate that, for the first time, there is a potential renal targeted treatment for kidney injury caused by cisplatin, a widely used...
Stress Makes Life’s Clock Tick Faster, Chilling Out Slows It Down
Neuroscience News2 hours ago Summary: Chronic stress accelerates the body’s epigenetic clock, however, those that can manage the effects of stress by strengthening their emotional regulation and self-control can slow the process. Source: Yale Scientists in recent years have developed ways to measure biological age by tracking chemical changes in DNA that occur naturally as people age...
Cleveland Clinic research identifies sildenafil as candidate drug for Alzheimer’s disease
CLEVELAND CLINIC IMAGE: ACCORDING TO FINDINGS PUBLISHED IN NATURE AGING, THE RESEARCH TEAM, LED BY FEIXIONG CHENG, PH.D., OF CLEVELAND CLINIC’S GENOMIC MEDICINE INSTITUTE, DETERMINED THAT SILDENAFIL IS ASSOCIATED WITH 69% REDUCED INCIDENCE OF ALZHEIMER’S DISEASE. CREDIT: CLEVELAND CLINIC December 6, 2021, CLEVELAND: A new Cleveland Clinic-led study has identified sildenafil – an FDA-approved therapy for erectile...
Study identifies factor in ‘young blood’ that helps rejuvenate aged mouse muscle
UNIVERSITY OF PITTSBURGH IMAGE: FABRISIA AMBROSIO, PH.D., DIRECTOR OF REHABILITATION FOR UPMC INTERNATIONAL AND ASSOCIATE PROFESSOR OF PHYSICAL MEDICINE AND REHABILITATION AT THE UNIVERSITY OF PITTSBURGH CREDIT: UPMC PITTSBURGH, Dec. 6, 2021 — As we age, our muscles gradually become smaller, weaker, and less able to heal after injury. In a new study, UPMC and...
Smoke screen: Analysis of saliva from long-term cannabis smokers identifies disruptions in the healthy oral microbiome that may lead to brain disorders
MEDICAL UNIVERSITY OF SOUTH CAROLINA IMAGE: WEI JIANG, M.D., IMMUNOLOGIST AND ASSOCIATE PROFESSOR IN THE DEPARTMENT OF MICROBIOLOGY AND IMMUNOLOGY AT THE MEDICAL UNIVERSITY OF SOUTH CAROLINA. CREDIT: SARAH PACK, MEDICAL UNIVERSITY OF SOUTH CAROLINA More and more states are legalizing marijuana, but little is known about how long-term cannabis use affects the microbes in...