by Karolinska Institutet Credit: Unsplash/CC0 Public Domain Researchers at Karolinska Institutet, University of Oslo, and Oslo University Hospital have developed a new kind of immunotherapy for leukemia. The results of a study published in Nature Biotechnology show that the therapy kills cancer cells from patients with acute lymphoblastic leukemia. The researchers now want to conduct...
Damage to a part of the brain that regulates hyperactivity can contribute to both memory problems and seizures in the most common form of epilepsy, according to research at the University of Wisconsin–Madison. The study, published recently in the Journal of Neuroscience, may lead to earlier diagnosis of epilepsy and possibly new ways to treat...
Senescent cells accumulate with age throughout the body, and contribute directly to the onset and progression of a wide range of age-related conditions. While never present in large numbers in comparison to normal somatic cells, senescent cells are metabolically active, secreting signals that provoke chronic inflammation, altered cell behavior, and numerous forms of tissue dysfunction....
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR), SINGAPORE IMAGE: AN INVASIVE GASTRIC TUMOUR CONTAINING LGR5-EXPRESSING STEM-LIKE CELLS (GREEN), SOME OF WHICH ARE ACTIVELY PROLIFERATING (MAGENTA). ELIMINATION OF THESE TUMOUR-RESIDENT LGR5-EXPRESSING POPULATIONS GREATLY REDUCES TUMOUR GROWTH AND SPREAD IN MICE. CREDIT: SOWMYA SAGIRAJU AND GRACE LIM, INSTITUTE OF MOLECULAR AND CELL BIOLOGY (IMCB), A*STAR SINGAPORE – Scientists...
REDHILL BIOPHARMA IMAGE: REDHILL’S OPAGANIB MECHANISM UNAFFECTED BY OMICRON MUTATIONS CREDIT: REDHILL BIOPHARMA TEL AVIV, Israel and RALEIGH, NC, December 6, 2021, RedHill Biopharma Ltd.(Nasdaq: RDHL) (“RedHill” or the “Company”), a specialty biopharmaceutical company, today announced that because opaganib’s proposed mechanism of action is not impacted by spike protein mutations, opaganib is expected to be...
KECK SCHOOL OF MEDICINE OF USC IMAGE: JUSTIN SCHAAL, Ph.D., ASSISTANT PROFESSOR OF RESEARCH PATHOLOGY AT THE KECK SCHOOL OF MEDICINE OF USC CREDIT: USC PHOTO/ RICARDO CARRASCO III Somewhere along the long and winding road of evolution, our ancestors lost the ability to produce a small but mighty group of molecules called theta-defensins that...
by Yasmin Anwar, University of California – Berkeley Figure 1. The emotional stop-signal task (ESST) instructs participants to rapidly indicate the valence of serially presented images by keypress, except on trials with an auditory stop-signal, when participants are asked to inhibit their emotional reaction and accompanying behavioral response. If participants are unable to inhibit an...
by Gina Wadas, Johns Hopkins University Credit: Pixabay/CC0 Public Domain The blood-brain barrier is an essential and meticulous protector of the human body. This highly selective gatekeeper of interlocking endothelial cells forms tight junctions, shielding vulnerable brains cells from toxins in the bloodstream. However, this also means that the BBB blocks many compounds from entering...
by Göttingen University The image shows neuronal cell nuclei of the dentus gyratus (yellow) and associated blood vessels (red). By varying the magnification of the X-ray optics, one can “zoom in” on the densely packed band of neurons (in the red oval) and also resolve the substructure of the cell nucleus (blue oval). The study...
UNIVERSITY OF PENNSYLVANIA SCHOOL OF NURSING IMAGE: SHOSHANA V. ARONOWITZ, Ph.D., MSHP, FNP-BC, ASSISTANT PROFESSOR IN PENN NURSING’S DEPARTMENT OF FAMILY AND COMMUNITY HEALTH CREDIT: SHOSHANA ARONOWITZ PHILADELPHIA (December 6, 2021) – The majority of individuals with opioid use disorder (OUD) face access barriers to evidence-based treatment. While the COVID-19 pandemic offered an opportunity to...
