Month: <span>February 2022</span>

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More effective COVID-19 treatment with immune modulatory drugs
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More effective COVID-19 treatment with immune modulatory drugs

by Chelsea Donohoe, CU Anschutz Medical Campus Fig. 1. IFN signaling at the whole-blood transcriptome level correlates with a subset of IFNs. (A) Volcano plot for differential mRNA expression analysis by COVID-19 status, adjusted for age and sex. Horizontal dashed line indicates a false-discovery rate (FDR) 10% for negative binomial Wald test; numbers above plot...

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Does improving sleep reduce signs of early Alzheimer’s disease?

Clinical trial seeks seniors with sleep issues but no cognitive problems. The TV sitcom grandpa character who always seems to fall asleep at unfortunate moments is so common it’s almost a cliché. But daytime napping and disjointed sleep at night aren’t normal parts of aging. Sleep disturbances can be an early sign of a neurodegenerative...

Making the invisible visible: A clearer ‘picture’ of blood vessels in health and disease thanks to new imaging approach
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Making the invisible visible: A clearer ‘picture’ of blood vessels in health and disease thanks to new imaging approach

JOHNS HOPKINS MEDICINE IMAGE: A STILL FROM THE VISUAL DEMONSTRATION OF THE RESULT OF THE VASCUVIZ IMAGING PIPELINE. CREDIT: CREDIT: JOHNS HOPKINS MEDICINE Johns Hopkins Medicine researchers have developed and tested a new imaging approach they say will accelerate imaging-based research in the lab by allowing investigators to capture images of blood vessels at different...

Antibiotic-prescribing algorithm cuts the risk of antibiotic resistance by half
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Antibiotic-prescribing algorithm cuts the risk of antibiotic resistance by half

by American Technion Society Credit: Unsplash/CC0 Public Domain Antibiotics are a double-edged sword: on the one hand, antibiotics are essential to curing bacterial infections. On the other, their use promotes the appearance and proliferation of antibiotic-resistant bacteria. Using genomic sequencing techniques and machine learning analysis of patient records, the researchers have developed an antibiotic prescribing...

Computer drug simulations offer warning about promising diabetes and cancer treatment
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Computer drug simulations offer warning about promising diabetes and cancer treatment

by University of Waterloo Credit: Unsplash/CC0 Public Domain Using computer drug simulations, researchers have found that doctors need to be wary of prescribing a particular treatment for all types of cancer and patients. The drug, called metformin, has traditionally been prescribed for diabetes but has been used in clinical settings as a cancer treatment in recent years....

Physical fitness linked to lower risk of Alzheimer’s disease
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Physical fitness linked to lower risk of Alzheimer’s disease

by American Academy of Neurology Credit: Pixabay/Pete Linforth. People who are more physically fit are less likely to develop Alzheimer’s disease than people who are less physically fit, according to a preliminary study released today, February 27, 2022, that will be presented at the American Academy of Neurology’s 74th Annual Meeting being held in person...

How long does protective immunity against COVID-19 last after infection or vaccination? Two immunologists explain
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How long does protective immunity against COVID-19 last after infection or vaccination? Two immunologists explain

by Prakash Nagarkatti, Mitzi Nagarkatti, The Conversation Credit: Unsplash/CC0 Public Domain As the omicron variant of SARS-CoV-2 took hold across the globe in late 2021, it became readily apparent that the pandemic had entered a new phase. Having experienced a previous COVID-19 infection or being vaccinated still left many people wondering how vulnerable they were...

Uncovering the genetic causes of fatty liver disease, which is a growing health concern
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Uncovering the genetic causes of fatty liver disease, which is a growing health concern

by Benoit Arsenault, Émilie Gobeil, The Conversation Studying the genetic aspects of fatty liver disease can help identify its causes and consequences and find new treatments. Credit: Shutterstock Over the past 40 years, changes in our urban environment and diet have had a major impact on our lifestyles. We are more sedentary and the quality...

Transgender youth on puberty blockers and gender-affirming hormones have lower rates of depression and suicidal thoughts
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Transgender youth on puberty blockers and gender-affirming hormones have lower rates of depression and suicidal thoughts

by Diana Tordoff, Arin Collin, The Conversation Credit: Unsplash/CC0 Public Domain Recent studies estimate that 1.8% to 2.7%—or approximately 750,000 to 1.1 million—adolescents in the U.S. identify as transgender or nonbinary. Many of these trans youth experience high levels of negative mental health symptoms due to anti-transgender stigma, discrimination and lack of family or peer support. A 2021 study found...