UNIVERSITY HOSPITALS OF LEICESTER NHS TRUST Patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) and a history of frequent ‘attacks’ who were given a medicine called astegolimab reported an increase in health-related quality of life compared to those on a placebo, according to findings from a study published in the Lancet Respiratory Medicine. The COPD-ST2OP trial...
Month: <span>March 2022</span>
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Study reveals decisive role of PDK1 enzyme in acute myeloid leukaemia
UNIVERSITY OF BARCELONA IMAGE: THE CONSOLIDATED RESEARCH GROUP ON INTEGRATIVE BIOCHEMISTRY, LED BY PROFESSOR MARTA CASCANTE (UB-IBUB). CREDIT: UNIVERSITY OF BARCELONA Acute myeloid leukaemia (AML) remains harder to treat therapeutically due to the high existing genetic heterogeneity not only between patients but also between the population of subclones of cancer cells within the same person....
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Structures involved in communication among pathogenic fungi could be targets for novel treatments
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO A group of scientists in Brazil and the United States has revealed the role played by certain structures in intermediating communication among individual fungi of the same species. The discovery, detailed in an article published in the journal mBio, could serve as the basis for...
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A nanomaterial that may improve insulin’s effects on the nervous system
by Emily Caldwell, The Ohio State University Insulin injections help with management of type 1 and type 2 diabetes. Ohio State researchers have developed a nanomaterial that may improve insulin’s effects on the nervous system. Credit: Shutterstock.com There may be a way in the future to enhance diabetes treatment—with better control of blood sugar and...
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Gene therapy helps heal deadly ‘butterfly children’ blistering condition
by Dennis Thompson An experimental cream-based gene therapy may soon become the first U.S. government-approved means for treating a rare and devastating skin disease that produces “butterfly children.” Patients with recessive dystrophic epidermolysis bullosa (EB) are called butterfly children “because their skin is as fragile as the wings of a butterfly,” explained lead researcher Dr....
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Researchers identify a potential window for treating ALS
by Johns Hopkins University School of Medicine Credit: Pixabay/CC0 Public Domain Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that affects as many as 30,000 people in the United States, with 5,000 new cases diagnosed each year. It weakens muscles over time, impacting physical function and ultimately leading to death. There is no single cause...
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Immune cells produce chemical messenger that prevents heart disease–related inflammation
by Michael Morrison, Massachusetts General Hospital Acetylcholine is produced by bone marrow B lymphocytes. Credit: Nature Immunology (2022). DOI: 10.1038/s41590-022-01165-7 The immune system’s white blood cells, which are produced in the bone marrow, mostly help to defend against bacteria and injury, but sometimes they can turn against the body—for example, in cardiovascular disease, their inflammatory aggression can...
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Osmotic pressure and viscosity: Anticancer drug efficacy and restricting tumors using LDDS
by Tohoku University Figure 1. The improvement of drug delivery of anticancer drugs by expansion of lymphatic sinus with high osmotic and high viscosity solvents from A to H. Credit: Tohoku University Chemotherapy is known for its painful side-effects. It also has limitations when the cancer has metastasized to the lymph nodes. The lymphatic drug...
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UV-LED lights can kill coronaviruses and HIV with the flip of a switch
by Alexa Battler, University of Toronto Christina Guzzo conducted her research in the Guzzo Lab, a viral immunology lab at U of T Scarborough that focuses partly on HIV. Credit: Ken Jones The same lightbulbs used in offices and public spaces can destroy coronaviruses and HIV, according to a new study from University of Toronto...
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How food and diet impact the treatment of disease
by The City University of New York Credit: Unsplash/CC0 Public Domain Today, the Center for Food As Medicine (famcenter.org) and the Hunter College NYC Food Policy Center (nycfoodpolicy.org) released its groundbreaking, 335 page (with more than 2500 citations), first ever, academic narrative review and report of the food as medicine movement, titled “Food As Medicine:...