by Hokkaido University Effect of palbociclib on ATLL tumors in mice. ATLL tumors grafted into mice were subjected to three treatments and compared to a control (far left). Treatment with palbociclib reduced the size of tumors (center left), while treatment with everolimus also reduced the size of the tumors (centre right). However, treatment with both...
by Texas Tech University Nadia German, Ph.D., (right) and collaborator Constantinos Mikelis, Ph.D., have received a U.S. patent for a chemical that targets the brain’s dopamine transporter. Credit: TTUHSC Many brain diseases and disorders lead to neuroinflammation, a swelling of brain tissue that is increasingly recognized as one ofthe telltale signs and disease progression factors...
by Zhang Nannan, Chinese Academy of Sciences Alpinia hainanensis. Credit: Ji Kailong Ulcerative colitis (UC) is a nonspecific, chronic and recurrent inflammatory bowel disease. Alpinia plants (Zingiberaceae family) are the ideal materials for finding therapeutic agents against UC. Alpinia hainanensis is an important food spice and ethnic medicine in Southwest China. However, there have been...
by International Society for Stem Cell Research Monkey iPSCs with edited CCR5 locus growing in culture. Credit: Saritha D’Souza, Wisconsin National Primate Research Center, USA Genetic engineering can make immune cells resistant to infection with human or monkey (simian) immunodeficiency virus (HIV and SIV, respectively). Recently, treatment with HIV-resistant immune cells has given encouraging results...
by Adrianna Rodriguez Credit: Unsplash/CC0 Public Domain You’ve heard about the dangers of secondhand cigarette smoke, but what about secondhand bong smoke? The haze after a bubbly bong hit may appear harmless, but a new study published Wednesday in JAMA Network Open found bystanders may be inhaling air pollutants at concentrations more than twice federal air quality...
by Amy Norton A noninvasive ultrasound technique is capable of quickly pulverizing kidney stones, an early study shows—in what researchers call a first step toward a simpler, anesthesia-free treatment for the painful problem. The study reports on the first 19 patients who’ve had kidney stones treated with the ultrasound “bursts.” So far, it’s been able...
by Kerry Noble, Imperial College London Adjusted HRs of COVID-19 hospitalization in children for different asthma status compared with children with no asthma. HRs of death COVID-19 hospitalization compared with people with no asthma, obtained from Cox regression models. Sociodemographic factors include, region, ethnicity, quintile of the Index of Multiple Deprivation. OCS, oral corticosteroids. Credit: Thorax (2022)....
by University of Texas Health Science Center at Houston Sunil A. Sheth, MD, associate professor of neurology with McGovern Medical School at UTHealth Houston. Credit: UTHealth Houston Using a 1-millimeter-sized wireless implant to stimulate peripheral nerves from within blood vessels has the potential to treat neuropathic pain resistant to medical therapy, according to a team...
Written by Anne Jacobson, MD, MPH | Reviewed by Patricia Pinto-Garcia, MD, MPH Published on March 4, 2022 Key takeaways: Some of us have to pee more often than others. Maybe you’ve wondered if you’re peeing too much or too little. Or maybe your bathroom schedule has changed. How much and how often you pee...
Written by Cherilyn Cecchini, MD | Reviewed by Katie E. Golden, MD Published on February 15, 2022 Key takeaways: Headaches can be scary, especially if you have never had a bad one before. But most headaches aren’t life-threatening or related to anything wrong with your brain. On rare occasions, a headache can be a symptom...
