Written by Sonia Amin Thomas, PharmD, BCOP | Reviewed by Joshua Murdock, PharmD Published on June 13, 2022 Key takeaways: Advil (ibuprofen) is an affordable over-the-counter (OTC) pain reliever and fever reducer available in many different formulations. Motrin is another well-known brand name for ibuprofen. Advil has a risk of long-term side effects, such as...
By Rich Haridy June 21, 2022 New research hypothesizes narrowing blood vessels in the brain plays a role in the cognitive decline associated with Alzheimer’s disease Depositphotos Following yet another failed clinical trial testing a novel drug designed to break up the aggregations of toxic proteins thought to be the cause of Alzheimer’s disease, a...
The measurements exceed accuracy levels of nearly all available options on the market today. Blood pressure is one of the most important indicators of heart health, but it’s tough to frequently and reliably measure outside of a clinical setting. For decades, cuff-based devices that constrict around the arm to give a reading have been the gold...
Research from the Division of Pulmonary and Critical Care Medicine was featured prominently at the recent conference of the American Thoracic Society, the leading medical society focused on global respiratory health. Here are a few highlights: New treatment for severe asthma A greater proportion of patients with severe, uncontrolled asthma had more significant clinical responses to a...
Cold Spring Harbor Laboratory (CSHL) Professor Hiro Furukawa takes an architectural approach to brain research. He creates structural 3D maps of important proteins that malfunction in brain disorders. Furukawa has zeroed in on a protein called the NMDA (for N-methyl-D-aspartate) receptor that plays a key role in learning and memory. The NMDA receptor acts as a channel to allow ions into neurons...
WILEY Previous studies have looked for links between glaucoma—a neurodegenerative disorder that’s the leading cause of irreversible blindness—and cognitive function, but they’ve generated mixed results. Findings from a large study recently published in the Journal of the American Geriatrics Society suggest that any association may be small or absent. In the study that included 7,073 US adults...
by Anne Rommel, Leibniz-Institut für Arbeitsforschung an der TU Dortmund Graphical abstract. Credit: Journal of Hepatology (2022). DOI: 10.1016/j.jhep.2022.01.020 Poisoning with paracetamol (acetaminophen—APAP) is a common cause of liver failure. However, not all the correlations that lead to liver damage from APAP are yet known. Especially the role of bile acids is unclear. The Leibniz Research Center...
by The Francis Crick Institute Red blood cells and white blood cells. Credit: Francis Crick Institute Researchers led by the Francis Crick Institute have found that blocking a particular protein could offer a new way to target leukemic stem cells without causing harm to healthy stem cells. More than 3,000 people are diagnosed with acute...
by Zhang Nannan, Chinese Academy of Sciences Schematic illustration of the mechanism of Oct4A palmitoylation promotes tumorigenicity and stemness in human glioblastoma cells. Credit: Chen Xueran Researchers led by Prof. Fang Zhiyou and Prof. Chen Xueran from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS), have found, for the first...
by Janos Krüger, Technische Universität Braunschweig Researchers Antonia Henne, Dr Wei He and Prof. Karsten Hiller at BRICS in Braunschweig. Credit: BRICS/TU Braunschweig A team of scientists led by Professor Karsten Hiller from the Braunschweig Center for Systems Biology BRICS has discovered an endogenous, anti-inflammatory substance: mesaconic acid. This molecule could be a drug candidate...
