by National Institutes of Health A microscopic view of salivary gland acinar epithelial cells (pink) infected with rotavirus (green), a type of enteric virus, in a mouse. Credit: Nihal Altan-Bonnet (NIH/NHLBI) A class of viruses known to cause severe diarrheal diseases—including the one famous for widespread outbreaks on cruise ships—can grow in the salivary glands...
Novel gene for Alzheimer’s disease in women identified
by Boston University School of Medicine This stylistic diagram shows a gene in relation to the double helix structure of DNA and to a chromosome (right). The chromosome is X-shaped because it is dividing. Introns are regions often found in eukaryote genes that are removed in the splicing process (after the DNA is transcribed into...
Targeting a human protein to squash SARS-CoV-2, other viruses
by American Chemical Society Apratoxin S4 (structure shown here) is effective against SARS-CoV-2 in human cells and could be a pan-viral therapeutic. Credit: Adapted from ACS Infectious Diseases 2022, DOI: 10.1021/acsinfecdis.2c00008 More than two years into the COVID-19 pandemic, people are realizing that the “new normal” will probably involve learning to co-exist with SARS-CoV-2. Some treatments are available,...
Protein discovered in Parkinson’s disease could lead to new treatments
by CU Anschutz Medical Campus Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia Currently, there are no disease modifying therapies for Parkinson’s disease that can change the progression of the disease. An international team of scientists led by faculty at the University of...
Surprise billing dispute resolution outcomes in Texas anchored to median in-network allowed amount
by University of Southern California Under the No Surprises Act, disputes between payers and providers are settled through arbitration while the patient is held harmless for any surprise bill that occurs in an emergency or in-patient setting during which the patient could not have reasonably known the provider was out-of-network. Under the law, arbiters are...
Only 1 in 5 people in the US has optimal heart health
by American Heart Association Credit: Pixabay/CC0 Public Domain About 80% of people in the U.S. have low to moderate cardiovascular health based on the American Heart Association’s new Life’s Essential 8 checklist according to a new study published today in Circulation journal. Life’s Essential 8, also published today in Circulation, details the Association’s updated guidance to measure cardiovascular health, adding...
American Heart Association adds sleep to cardiovascular health checklist
by American Heart Association Credit: CC0 Public Domain Sleep duration is now considered an essential component for ideal heart and brain health. Life’s Essential 8 cardiovascular health score replaces Life’s Simple 7, according to a new Presidential Advisory, Life’s Essential 8—Updating and Enhancing the American Heart Association’s Construct on Cardiovascular Health, published today in Circulation journal. Other updates...
New technique for detecting typhoid infections faster, which is more accurate than conventional testing
by UC Davis Estimated seroincidence of typhoidal Salmonella by study community and age group. Age groups are denoted by point shapes for the median, with lines indicating the 95% CI. Boxes reflect the height of the median estimate for the overall population-based serosurvey. Credit: The Lancet Microbe (2022). DOI: 10.1016/S2666-5247(22)00114-8 An international team of researchers found a...
Many drugs can’t withstand stomach acid. A new delivery method could lead to more convenient medications
by Khatcher O. Margossian and Murugappan Muthukumar, The Conversation pZC is designed to stay enveloped around its drug cargo in highly acidic environments, as in the stomach, and disassemble in less acidic environments, as in the small intestine. Credit: Khatcher Margossian, CC BY For patients and physicians, taking medications orally is often the most desirable way to...
Research sheds light on mechanism by which long-term anti-anxiety drug use affects the brain
by Australian Nuclear Science and Technology Organisation (ANSTO) Credit: Pixabay/CC0 Public Domain ANSTO health researchers have contributed to an international study published in Nature Neuroscience that sheds light on the mechanism by which anti-anxiety drugs act on the brain which could lead to cognitive impairment in vulnerable individuals. The research critically depended on a unique laboratory model developed...