by Marjorie Montanez-Wiscovich and Arthur Mark Samia, The Conversation Cellulitis of left leg, demarcated, about 24 hours after onset of symptoms. Bacteria likely entered via a small psoriasis fissure. Credit: Stephen Ewen/Wikimedia Commons, CC BY-SA 4.0 Your skin usually deflects any bacteria it encounters, protecting you from all sorts of infections. However, when you get a bug...
by Delthia Ricks, Medical Xpress scRNAseq replicates. CD45.1+ P14 cells were adoptively transferred into adult CD45.2+ GP or GFAP:GP mice 24h before i.c. infection with rLCMV-GP33. At least six weeks later, mice were treated with antiCD8a depleting antibody or isotype control. One week after depletion, mice were treated with TAM i.p. for four consecutive days...
by Penn State College of Medicine Simulation studies comparing the performance of PUMICE to other TWAS methods. Panels (a, b) illustrates the comparison of PUMICE to other single-tissue TWAS methods for type I error (a) and power (b). Panels (c, d) illustrates the comparison of PUMICE to multi-tissue TWAS method (UTMOST) for type I error...
by Stefan Zorn, Medizinische Hochschule Hannover Credit: CC0 Public Domain About 1% of the world’s adult population suffers from pulmonary hypertension (PH). Among the many forms of this disease is idiopathic pulmonary arterial hypertension (IPAH), a rare but very severe disease. The term “idiopathic” means that there is no tangible cause for the disease. A...
by Lisa Graham-Wisener, The Conversation People find it difficult to talk about death. Credit: Shutterstock When it comes to talking about death, we have no shortage of euphemisms. This is perhaps most famously illustrated in Monty Python’s dead parrot sketch from 1971. A pet shop worker insists to a customer that his new parrot is “not...
By Julia Evangelou Strait, Washington University School of Medicine in St. Louis Graphical abstract. Credit: Cell (2022). DOI: 10.1016/j.cell.2022.06.004 A new study from Washington University School of Medicine in St. Louis demonstrates that certain human gut microbes can mine dietary fiber to extract nutrients that otherwise would remain inaccessible to the human body. The study, published June...
by Patricia Riddell, The Conversation Catastrophising can lead to undue stress and anxiety. Credit: Rawpixel.com/ Shutterstock Imagine you have an interview for a new job tomorrow. Some people might think about what kind of questions they will be asked so that they can prepare, or imagine the interview going well. For others, the thought of an...
by Sara Senoner, Eurac Research MedSENS device. Credit: Martina Jaider, Eurac Research During an emergency medical intervention, measuring vital parameters is not always possible. Victims are often uncooperative, spaces uncomfortable and the equipment one can carry very limited—just think of a helicopter rescue or the scene of a car accident. Eurac Research in collaboration with...
by Will Doss, Northwestern University Credit: Pixabay/CC0 Public Domain Epigenetic biomarkers may reflect past cardiovascular health exposures and predict cardiovascular disease in the future, according to a Northwestern Medicine study published in the journal Circulation. These biomarkers measured around midlife reveal valuable health information from a patient’s past, according to Yinan Zheng, Ph.D., assistant professor of Preventive...
by Pai Liu, Michigan State University Graphical abstract. Credit: Molecular Therapy – Oncolytics (2021). DOI: 10.1016/j.omto.2021.12.004 Advancements in cancer research and treatment have resulted in great improvements in survival rates—today, there are almost 17 million people in the United States alone who have survived their diagnosis because of the physicians and scientists who have dedicated their careers to...
