by University of Otago Credit: Pixabay/CC0 Public Domain The past two years have caused widespread disruption, anxiety, loss and grief worldwide—but a new University of Otago, Christchurch, study has identified a concerning link between ongoing COVID‑19 disruption and worsening mental health for those most at risk. The international study, involving hundreds of New Zealanders, has...
Biochemists use enzymes to change how brain cells communicate with each other
by Anne Manning, Colorado State University GABAergic synapse properties are modulated by GABAAR activity. a Experimental strategy for panels b–f; NV57 neurons were incubated with synaptic inhibitors, half-exchanged media every other day from post-induction day 4–5 to day 56–60, and analyzed afterwards as indicated (arrow). b, c Sample images (left) and normalized density or size...
Oral pill taken once a day improves outcomes of patients with myelofibrosis
Reviewed by Emily Henderson, B.Sc. Jun 7 2022 Momelotinib, an oral pill taken once a day, significantly improved outcomes of patients treated for myelofibrosis (MF), a rare but fatal bone marrow cancer, researchers reported June 7. Ruben Mesa, MD, FACP, executive director of the Mays Cancer Center, home to UT Health San Antonio MD Anderson...
LIGHT POWERS NANO-DRILLS THAT KILL BACTERIA
These molecular machines have also proven effective at killing bacteria through tests on real infections. Rice University chemist James Tour and his team successfully tested six variants of molecular machines. All of them punched holes in the membranes of gram-negative and gram-positive bacteria in as little as two minutes. Resistance was futile for bacteria that...
WHY PIGMENT DOESN’T ALWAYS RETURN IN VITILIGO
The study appears in the journal JCI Insight. “In this study, we couple advanced imaging with transcriptomics and bioinformatics to discover the cell-to-cell communication networks between keratinocytes, immune cells and melanocytes that drive inflammation and prevent re-pigmentation caused by vitiligo,” says Anand K. Ganesan, professor of dermatology and vice chair for dermatology research at the University...
Treating sarcoidosis with JAK inhibitor shows promise in clinical trial
Every patient in a Yale clinical trial of a new treatment for the disfiguring disease sarcoidosis saw an improvement in their skin — and more than half showed improvement in affected internal organs. Sarcoidosis is a disease affecting four out of every 10,000 people in the United States. In sarcoidosis, abnormal collections of immune cells called granulomas...
Weight lifting for looks may result in reverse anorexia
People exercise for many different reasons, including looks. Gyms are full in cities and people make sure to make time in their busy schedules to exercise. Weight lifting is a common type of exercise, particularly popular among men. However, scientists at the University of Queensland urge people to be careful – those who are lifting...
Virtual Reality to Train Staff to Deal with Agitated Patients
JUNE 6TH, 2022 CONN HASTINGS EDUCATION, ETC. Researchers at the National University of Singapore, Yong Loo Lin School of Medicine, have developed a virtual reality training system that lets healthcare staff learn how to deal with agitated or aggressive patients. Patients, particularly with mental health issues, can become angry and distressed, and learning to handle such...
Researchers use nanotechnology to destroy and prevent relapse of solid tumour cancers
NATIONAL UNIVERSITY OF SINGAPORE, YONG LOO LIN SCHOOL OF MEDICINE As people across the globe look forward to longer life expectancies, malignant cancers continue to pose threats to human health. The exploration and development of immunotherapy aims to seek new breakthroughs for the treatment of solid tumours. The successful establishment of anti-tumour immunity requires the...
Long-term study finds cigarette smoking doubled risk of developing heart failure
JOHNS HOPKINS UNIVERSITY BLOOMBERG SCHOOL OF PUBLIC HEALTH A new study from researchers at the Johns Hopkins Bloomberg School of Public Health found that people who smoked tobacco cigarettes developed heart failure at twice the rate of those who never smoked. This higher rate occurred in two major heart failure subtypes and confirms that cigarette...