BETH ISRAEL DEACONESS MEDICAL CENTER BOSTON — By the year 2030, pancreatic cancer is expected to become the second most common cause of cancer deaths for both men and women in the United States, according to recent reports. While considered uncommon, inherited gene mutations can increase a person’s risk of developing pancreatic cancer. Early detection...
Month: <span>June 2022</span>
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Bone, heal thyself: Toward ceramics tailored for optimized bone self-repair
by Tokyo Medical and Dental University Transformation of a salt of calcium ions and phosphate esters into hydroxyapatite mediated by alkaline phosphatase (ALP). Credit: Department of Inorganic Biomaterials, TMDU Your chance of breaking a bone sometime within the next year is nearly 4%. If you’re unlucky enough to need a bone replacement, it’ll probably be...
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Fecal transplant throws new light on inflammatory bowel disease
by University of Groningen How the adoptive transfer of altered gut microbiota is sufficient to disrupt/restore intestinal tissue homeostasis. Credit: Markus Schwalbe and Sahar El Aidy, University of Groningen Inflammatory bowel disease is accompanied by a number of changes in the intestines, such as a change in epithelial permeability, a change in the composition of...
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New data align with EULAR recommendations for fibromyalgia management
by European Alliance of Associations for Rheumatology (EULAR) Credit: Unsplash/CC0 Public Domain Dr. Philip Lage-Hansen and colleagues used the EULAR Congress to share their new data on the prevalence of fulfillment of survey-based criteria for fibromyalgia among 248 newly referred patients in a rheumatic outpatient clinic. This observational cohort study also aimed to compare the...
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Oxygen saturation overestimated in minority COVID-19 patients
Asian, Black, and Hispanic patients with COVID-19 have persistent overestimation of arterial oxygen saturation, according to a study published online May 31 in JAMA Internal Medicine. Ashraf Fawzy, M.D., M.P.H., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues conducted a retrospective cohort study of clinical data for COVID-19 patients who self-identified as...
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Novel approach identifies highly specific anti-cancer compounds
by Baylor College of Medicine Credit: Unsplash/CC0 Public Domain Researchers at Baylor College of Medicine and Texas Children’s Hospital have identified potent, highly specific compounds that interfere with bromodomain (BD)-containing proteins involved in cancer. The compounds, called BET BD1-inhibitors, are a starting point in the development of potentially more effective anti-cancer drugs with less side...
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Research sheds light on why not all obese patients develop type 2 diabetes
by Oregon State University Credit: Pixabay/CC0 Public Domain Researchers at Oregon State University have invented a new analytical method that sheds light on an enduring mystery regarding type 2 diabetes: Why some obese patients develop the disease and others don’t. Type 2 diabetes is a serious metabolic disease that affects roughly one in 10 Americans. Formerly known...
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Bristol Myers’ autoimmune drug shows potential in lupus
Published June 1, 2022 Permission granted by Bristol-Myers Squibb Dive Brief: Bristol Myers Squibb’s experimental autoimmune disease drug deucravacitinib helped treat moderate-to-severe lupus in a Phase 2 trial, the company reported Wednesday. Results, which were presented at a medical conference in Denmark, showed two doses of the pill led to significantly higher response rates than did...
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Does He Have Back Pain or Rheumatism?
Julia Rommelfanger May 18, 2022 WIESBADEN, Germany — To differentiate temporary or even long-lasting symptoms, such as in the back, from one of the 100 or so “actual” rheumatologic conditions is not easy, even for specialists. “Inflammatory conditions of the connective tissue, which pervades the body, can be found throughout, in joints, muscles, vessels, organs,”...
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Long COVID Neuropsychiatric Deficits Greater Than Expected
Nancy A. Melville May 31, 2022 NEW ORLEANS – Patients experiencing brain fog and other persistent symptoms of long COVID show significant deficits on neuropsychiatric testing that correspond with prior acute COVID-19 infection, adding to mounting evidence of the significant toll the chronic condition can have on mental health. “Many clinicians have observed the symptoms...