H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE TAMPA, Fla. — The number of new cancer treatment options has increased tremendously over the past 20 years, resulting in significant improvements in patient outcomes. Despite these improved therapies, most patients will eventually develop drug resistance and disease recurrence. Scientists continue to develop new drugs and drug combinations...
Month: <span>June 2022</span>
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Researchers find two FDA-approved drugs that curb symptoms of Alzheimer’s disease
UNIVERSITY OF COLORADO ANSCHUTZ MEDICAL CAMPUS Two commonly used psychiatric drugs show evidence of improving symptoms of Alzheimer’s disease including boosting cognition, according to a study from researchers at the University of Colorado Anschutz Medical Campus. “The people who received these drugs developed better cognition and actually improved in their clinical diagnosis,” said the study’s senior...
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UCalgary researchers with the Calgary Stroke Program make another breakthrough in the treatment of stroke
UNIVERSITY OF CALGARY In the largest stroke clinical trial ever run in Canada, researchers have shown Tenecteplase (TNK), a safe, well tolerated drug, commonly used as a clot buster for heart attacks, is an effective treatment for acute ischemic stroke. Led by researchers with the University of Calgary at the Foothills Medical Centre and Sunnybrook...
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Scientists discover mechanism controlling spread of pancreatic cancer
INSTITUTE OF CANCER RESEARCH Key protein identified that helps turn pancreatic cancer cells into more aggressive form Pattern of cells in pancreatic tumours follows mathematical law first proposed by Alan Turing Fundamental discovery could pave way for new pancreatic cancer treatments Scientists have shown it is possible to reverse a key process that allows pancreatic...
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New method based on smart materials for experimenting with cells
UNIVERSIDAD CARLOS III DE MADRID IMAGE: THE TOP IMAGE SHOWS THE FORCES GENERATED BY AN EXTERNAL MAGNETIC FIELD ON PARTICLES EMBEDDED IN THE MATERIAL. THESE INTERACTIONS ARE SIMULATED BY A COMPUTATIONAL MODEL THAT IS ABLE TO GUIDE THE MANUFACTURING AND EXPERIMENTAL PROCESS (MIDDLE IMAGE). FINALLY, THE GENERATED FORCES ARE TRANSMITTED TO THE CELLS CULTURED ON...
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Boot camp for the immune system: How immune cells learn to discern friend from foe
by Ekaterina Pesheva, Harvard Medical School New research shows thymus cells assume various identities to teach nascent T cells how to distinguish friend from foe. Credit: Daniel Michelson, Mathis/Benoist Lab, Harvard Medical School The human immune system is a nearly perfect defense mechanism. It protects the body from disease-causing bacteria, viruses, and other pathogens. It detects...
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Precision antibacterials
UNIVERSITY OF WÜRZBURG IMAGE: PROF. DR. JÖRG VOGEL AND DR. LINDA POPELLA CREDIT: BRITTA GRIGULL / HIRI In the fight against the Covid-19 pandemic, mRNA-based vaccines have impressively demonstrated their potential. Using this technology, scientists were able to rapidly develop and bring to market vaccines against SARS-CoV-2 that have been extremely effective at protecting millions...
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Trial of potential universal flu vaccine opens at NIH Clinical Center
NIH/NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES IMAGE: VOLUNTEER IN TRIAL OF CANDIDATE UNIVERSAL FLU VACCINE BPL-1357 RECEIVES AN INTRAMUSCULAR INJECTION. CREDIT: NIAID A Phase 1 clinical trial of a novel influenza vaccine has begun inoculating healthy adult volunteers at the National Institutes of Health Clinical Center in Bethesda, Maryland. The placebo-controlled trial will test...
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Study reveals how Duchenne muscular dystrophy causes heart rhythm problems
ELIFE IMAGE: STEM CELL-DERIVED CARDIOMYOCYTES PRODUCED TO STUDY ARRHYTHMIC MECHANISMS CREDIT: FÁTIMA LOIS The results help explain why as many as 60% of patients with DMD have potentially life-threatening heart rhythm abnormalities. They may also suggest potential treatment strategies for heart problems in people with DMD. Mutations in a gene that encodes a muscle-protecting protein...
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Defining plasma dose for potential future cancer treatments
AMERICAN INSTITUTE OF PHYSICS IMAGE: PLASMA-ACTIVATED MEDIUM FOR CANCER TREATMENT. CREDIT: HE CHENG, JINGYI LUO, KE SONG, FENG ZHAO, DAWEI LIU, LANLAN NIE, AND XINPEI LU WASHINGTON, June 28, 2022 – Chinese researchers may have found a new approach to treat cancer by using a plasma treatment to induce apoptosis, the death of cancer cells,...