by Robert H. Shmerling, Harvard University While rainstorms improve conditions for those with allergies or asthma, a new study finds that thunderstorms can aggravate symptoms. Credit: Michael D./Unsplash It’s an old line: “Everyone complains about the weather but no one is doing anything about it.” But if you’re a person with bad allergies or asthma, stormy...
Researchers determine first crystal structure of LAG3 protein; findings could yield better cancer therapy approaches
by H. Lee Moffitt Cancer Center & Research Institute LAG3 Crystal Structure. Credit: Moffitt Cancer Center Immune checkpoint inhibitors have revolutionized cancer care. The therapy works by preventing tumors from shutting down the immune response, which in turn allows T cells to kill cancer cells. Established checkpoint inhibitors target the proteins PD-1 and CTLA-4 and...
Genetic variant may increase risk for CTE severity among older individuals with repetitive head impacts
by Boston University School of Medicine Credit: Pixabay/CC0 Public Domain How could two individuals who both played football for 10 years and developed CTE have different disease severity? How could some individuals develop dementia in their 50’s while other never develop dementia at all? Perhaps the answer lies in their genes. Repetitive head impact (RHI)...
Is this a way to stop Parkinson’s tremors? Inventor is convinced her creation can help thousands like her who are afflicted by the incurable condition
By ANGELA EPSTEIN FOR THE DAILY MAIL PUBLISHED: 19:46 EDT, 27 June 2022 | UPDATED: 10:24 EDT, 28 June 2022 The casual observer might easily overlook the small sprig of wire hooked over Sandra McDonough’s left ear. Yet this seemingly innocuous home-made little stick has, she claims, given her back the speech and mobility she lost after being diagnosed with...
Cost of brand-name epilepsy drugs increased by 277% over 8 years
The cost of all brand-name drugs for epilepsy paid by the Medicare system increased by 277% from 2010 to 2018, according to a new study from a University of Michigan team. During that same time, the amount that Medicare paid for generic drugs for epilepsy decreased by 42%, the team reports in a paper published online in Neurology, the medical...
Scientists blend AI, 3D tissue imaging to identify aggressive prostate cancer
Researchers at Case Western Reserve University and the University of Washington expect to gain valuable new insights into highly aggressive prostate cancer by combining Artificial Intelligence (AI)-powered diagnostic imaging with three-dimensional (3D) tissue imaging. This new AI-3D collaboration will provide a never-before-seen, expanded view and understanding of prostate cancer cells, made possible by a new approach...
Common antiretroviral drug improves cognition in mouse model of Down syndrome
by Center for Genomic Regulation Antiretroviral medication lamivudine pictured at the IrsiCaixa AIDS research institute in Barcelona. Credit: IrsiCaixa Lamivudine, a commonly-used antiretroviral drug for treating HIV, improves cognition in a mouse model of Down syndrome, according to the findings of a joint new study by researchers at the Centre for Genomic Regulation (CRG) and...
A reference tissue atlas for the human kidney
by Thamarasee Jeewandara , Medical Xpress An interactive cellular atlas representing the glomerulus and renal capsule of the kidney. Image downloaded via https://atlas.kpmp.org/explorer/ Credit: Science Advances (2022). DOI: 10.1126/sciadv.abn4965 A team of researchers including Jens Hansen, Rachel Sealfon, Rajastree Menon, and colleagues of the Kidney Precision Medicine Project, built on an existing specific human kidney tissue atlas relevant to...
Functional connections between different brain networks can predict a person’s age
by Ingrid Fadelli , Medical Xpress Credit: Pixabay/CC0 Public Domain Neuroscientists have been trying to understand for decades how the human brain changes over the lifespan. This could ultimately help to devise more effective treatments for neurological and cognitive disorders primarily observed in the elderly. Researchers at Drexel University and Villanova University have recently carried...
Researchers look at space between nerves and tumor cells to identify most aggressive oral cancers
by University of Michigan Credit: University of Michigan One of the most terrifying aspects of cancer is its unpredictability: Some cancerous tumors are cured by treatment, while others shrink with treatment only to return later. A new University of Michigan study identifies a feature in cancer that could help pinpoint treatment-resistant tumors when they are diagnosed,...