by Canadian Medical Association Journal A colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAID The antiviral drugs molnupiravir and nirmatrelvir–ritonavir (Paxlovid), when used to treat nonsevere COVID-19, most likely reduce the risk of subsequent progression to hospitalization and death, according to new research published in CMAJ (Canadian Medical Association Journal). As most trials have focused...
by Thomas Jefferson University Credit: Pixabay/CC0 Public Domain Lead exposure in early childhood can lead to severe cognitive and behavioral impairments in children that last well into adolescence and adulthood. Although researchers have looked at effects of early life lead exposure on a small number of genes involved in learning, memory, and brain development, research...
by Joel Streed, Mayo Clinic Credit: Mayo Clinic Exertional compartment syndrome is a medical condition that generally affects runners and people involved in jumping and impact sports. Symptoms may include pain, tightness, and weakness in the lower extremities. For some, physical therapy may help. Others may need more intensive treatment. Muscle groups are surrounded or...
by Delthia Ricks , Medical Xpress PD-1 dependent NK cell regulation of CD8+T-cells. C57BL/6 mice were infected with an adenoviral vector encoding the HBV genome and treated with anti-NK1.1 (⍺NK) or isotype control antibody prior to therapeutic vaccination. Intrahepatic lymphocytes were harvested 14 days after immunization. (A) Quantitative real-time PCR analysis of HBsAg mRNA extracted...
by Medical Journal of Australia Credit: Pixabay/CC0 Public Domain Sodium–glucose cotransporter 2 (SGLT2) inhibitors, such as empagliflozin, dapagliflozin, canagliflozin and ertugliflozin, have been game changers in the treatment of type 2 diabetes, but their potential for closing the mortality gap in type 1 diabetes has been a regulatory minefield, according to the authors of a...
by Loren Smith, University of Sydney Parts of the brain affected in PPA. The different colours represent the areas most affected in each PPA subtype (non-fluent variant: green; logopenic variant: purple; semantic variant: blue). Credit: University of Sydney Researchers and clinicians at the University of Sydney’s Brain and Mind Center have developed a free, online,...
By CAMERON HENDERSON FOR THE MAIL ON SUNDAY PUBLISHED: 17:00 EDT, 23 July 2022 | UPDATED: 17:12 EDT, 23 July 2022 Artificial intelligence can dramatically improve the chances of picking up the early-warning signs of oesophageal cancer, a pioneering NHS programme has shown. The computer technology works by analysing pictures taken during a procedure known as an endoscopy, when a tiny camera...
by Hokkaido University Oxidized-LDL accumulates (left column) in malignant tumors (bottom) much more than in non-malignant ones (top). This attracts neutrophils (right column, red) to malignant tumors (bottom), but not to non-malignant ones. Credit: Takuya Tsumita, et al. International Journal of Cancer. May 24, 2022 A key molecule for cancer metastasis has been identified as a molecule...
By Helen Branswell July 23, 2022 Colorized transmission electron micrograph of monkeypox virus particles. NIAID The World Health Organization on Saturday declared the unprecedented monkeypox outbreak that has spread around the world a public health emergency, a decision that will empower the agency to take additional measures to try to curb the virus’s spread. In an unusual...
by Osaka University Fig. 1. Amount of hydrogen generated per 1 g of the mouse gastrointestinal tract in the control group compared with in the mice given the silicon (Si)-based agent. Credit: Scientific Reports (2022). DOI: 10.1038/s41598-022-13655-7 Many people worldwide suffer from a chronic type of inflammatory bowel disease (IBD) called ulcerative colitis (UC), which is characterized by...
