Month: <span>July 2022</span>

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Histamine-producing gut bacteria can trigger chronic abdominal pain
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Histamine-producing gut bacteria can trigger chronic abdominal pain

by  McMaster University Illustration of bacteria in the human gut. Credit: Darryl Leja, National Human Genome Research Institute, National Institutes of Health Researchers from McMaster University and Queen’s University have discovered a gut bacterial “super-producer” of histamine that can cause pain flare-ups in some patients with irritable bowel syndrome (IBS). The culprit is what has now...

Study identifies new links between REM sleep disturbances and drug relapse
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Study identifies new links between REM sleep disturbances and drug relapse

by  Elsevier Credit: Pixabay/CC0 Public Domain Relapse presents a major barrier to recovery from substance use disorders—when people begin taking drugs such as cocaine again after a period of abstinence. Sleep disruptions have long been associated with drug withdrawal and relapse. Now, a new study provides a more detailed picture of recovery-related sleep that could lead...

Vitamin B5 activates brown fat, aids weight loss in mice
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Vitamin B5 activates brown fat, aids weight loss in mice

by  American Physiological Society Graphical abstract. Credit: American Journal of Physiology-Endocrinology and Metabolism (2022). DOI: 10.1152/ajpendo.00293.2021 Pantothenate acid, also known as vitamin B5, stimulated the production of brown fat in both cell cultures and mice, a new study finds. The study is published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism. It was chosen as an...

People respond differently to psychedelic drugs—genetics could be the reason
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People respond differently to psychedelic drugs—genetics could be the reason

by  American Chemical Society Credit: Pixabay/CC0 Public Domain Cluster headaches, anxiety and depression can be debilitating for people living with these conditions. Psychedelic drugs have shown benefits as treatments for these conditions in clinical studies, but not for everyone. Now, in ACS Chemical Neuroscience, researchers report that one reason could be common genetic variations in one serotonin...

Promising eco-friendly plug to treat nosebleeds
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Promising eco-friendly plug to treat nosebleeds

by University of the Basque Country Nasal plugs to tackle nosebleeds developed from food industry waste. Credit: Nagore Iraola, UPV/EHU Nosebleeds, also known as epistaxis, are one of the most frequent otolaryngologic (ENT) emergencies worldwide. It is estimated that 60% of the world’s population will experience an episode of epistaxis at least once in their...

Enzyme linked to most prevalent mutational signatures in cancer cell lines
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Enzyme linked to most prevalent mutational signatures in cancer cell lines

by Bob Yirka, Medical Xpress Using human cancer cell lines to investigate the origins of APOBEC3-associated mutagenesis. a, The experimental design used to track mutation acquisition in vitro over specific timeframes. The schematic was generated using BioRender. b, Profiles of APOBEC-associated signatures (sig.) extracted from SBSs identified across mutational catalogs of 5 stock cell lines...

Progress toward a stem cell–based therapy for blindness
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Progress toward a stem cell–based therapy for blindness

by Katherine Unger Baillie, University of Pennsylvania Following a transplantation procedure, human photoreceptor precursor cells labeled red migrated and integrated into a degenerated canine retina. The green label is a synaptic maker, suggesting the transplanted cells began forming a connection with second-order neurons in the retina. Credit: Beltran laboratory/Stem Cell Reports What if, in people...

Specialized brain regions recognize vocal cues that don’t involve speech
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Specialized brain regions recognize vocal cues that don’t involve speech

UNIVERSITY OF PITTSBURGH IMAGE: DISTINCT REGIONS OF THE AUDITORY CORTEX LOCATED IN SUPERIOR TEMPORAL GYRUS AND SUPERIOR TEMPORAL SULCUS ARE SPECIALIZED AT RECOGNIZING VOICE SOUNDS (SHOWN IN DARK BLUE) AND DO NOT RESPOND TO NON-VOICE ACOUSTIC SIGNALS. CREDIT: KYLE RUPP AND TAYLOR ABEL PITTSBURGH, July 28, 2022 – Specific parts of the brain recognize complex cues...

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Two in five eligible children in India missing out on preventive vitamin A

BMJ Two in five eligible children in India are missing out on preventive vitamin A supplementation designed to ward off the health problems associated with deficiency of the vitamin, finds an analysis of representative survey data, published in the open access journal BMJ Global Health. There are a large number of ‘cold spots’ in provision across...

MIT engineers develop stickers that can see inside the body
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MIT engineers develop stickers that can see inside the body

MASSACHUSETTS INSTITUTE OF TECHNOLOGY IMAGE: MIT ENGINEERS DESIGNED AN ADHESIVE PATCH THAT PRODUCES ULTRASOUND IMAGES OF THE BODY. THE STAMP-SIZED DEVICE STICKS TO SKIN AND CAN PROVIDE CONTINUOUS ULTRASOUND IMAGING OF INTERNAL ORGANS FOR 48 HOURS. CREDIT: IMAGE: FELICE FRANKEL Ultrasound imaging is a safe and noninvasive window into the body’s workings, providing clinicians with...