by Johns Hopkins University School of Medicine Credit: Pixabay/CC0 Public Domain Adults with abnormal heart metabolism are up to three times more likely to experience life-threatening arrhythmias (an irregular heart rhythm), and MRI techniques could be used to detect the condition and predict future sudden cardiac death (SCD), according to a small, but rigorous study...
Research shows investigational drug fosters nerve repair after injury
by University of Birmingham Credit: Unsplash/CC0 Public Domain Scientists from the University of Birmingham have shown that a brain-penetrating candidate drug currently in development as a cancer therapy can foster regeneration of damaged nerves after spinal trauma. The research, published today in Clinical and Translational Medicine, used cell and animal models to demonstrate that when taken orally...
Could a computer diagnose Alzheimer’s disease and dementia?
by Gina Mantica, Boston University Credit: Pixabay/CC0 Public Domain It takes a lot of time—and money—to diagnose Alzheimer’s disease. After running lengthy in-person neuropsychological exams, clinicians have to transcribe, review, and analyze every response in detail. But researchers at Boston University have developed a new tool that could automate the process and eventually allow it...
Preclinical study: Three-step treatment strategy for pancreatic cancer
by Cedars-Sinai Medical Center Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domain Research led by investigators at Cedars-Sinai Cancer and Johns Hopkins University have discovered a novel three-step treatment that disrupts the pancreatic tumor microenvironment in laboratory mice. The preclinical study, published in the journal Gastroenterology, focuses on a trio...
Researchers show effectiveness of migraine drug for weight loss in mice
by UT Southwestern Medical Center Credit: Pixabay/CC0 Public Domain Triptans, a commonly prescribed class of migraine drugs, may also be useful in treating obesity, a new study by scientists at UT Southwestern suggests. In studies on obese mice, a daily dose of a triptan led animals to eat less food and lose weight over the...
New research provides insight into Long COVID and ME
by University of Otago Credit: Unsplash/CC0 Public Domain Researchers have uncovered how post-viral fatigue syndromes, including Long COVID, become life-changing diseases and why patients suffer frequent relapses. Arising commonly from a viral infection, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), is known to cause brain-centered symptoms of neuroinflammation, loss of homeostasis, brain fog, lack of refreshing sleep,...
People of East Asian descent have more vessels reclog after endovascular treatment
by American Heart Association Credit: CC0 Public Domain Among people who received endovascular therapy to mechanically remove a clot in their large brain artery, those who had a rare genetic variant found primarily in people of East Asian descent (Japanese, Chinese and Korean) were more likely to have the vessel reclog during or shortly after...
Popular Malaysian soup can cause liver damage when mixed with medication
by Lee Gaskin, University of Adelaide The effect of four different bak kut teh formulations on HepG2 cells after 48 h of exposure. A Formulation #1 showed significant toxicity before dilution (p = 0.023), but demonstrated no significant toxicity once diluted (p > 0.05). B Formulation #2 demonstrated significant toxicity with no dilution factor (p = 0.009), but none once diluted...
Two different white blood cell types play opposing roles in affecting heartbeat irregularities after heart attack
by Michael Morrison, Massachusetts General Hospital Summary of findings. Credit: Nature Cardiovascular Research (2022). DOI: 10.1038/s44161-022-00094-w Patients with heart disease are at risk of experiencing a potentially lethal “electrical storm” involving recurrent episodes of a type of irregular heartbeat called ventricular tachycardia (VT). Electric shock therapy is used to treat VT following a heart attack, but unfortunately,...
Sunlight exposure found to trigger increased eating in men
by Bob Yirka, Medical Xpress Solar exposure enhances the energy intake and metabolic profile of men compared to women. a, Dot plot of the monthly energy intake (Kcal per day), from 1999 to 2001, of 2,991 men (cyan blue) and women (pink) (top). Midline represents the median. Data are presented as mean ± SD. Men’s energy consumption...