By Sandra G. Boodman July 9, 2022 at 7:17 a.m. EDT For as far back as he can remember, Aaron Blocker’s bones had given him trouble. Born with severely bowed legs, Blocker as a baby wore metal leg braces while he slept, which enabled him to walk. Even so, he said, his legs “always hurt.”...
Month: <span>July 2022</span>
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Scientists design a cheap device that can detect ear problems with the help of a smartphone
By Edward ChenJuly 8, 2022 ADOBE On a chilly October evening a decade ago, physician Michael Cohen arrived at Boston’s Logan International Airport lugging a hefty contraption, built like a tiny tank, that immediately drew the attention of airport security officers. It was a device to detect ear problems, and he and a colleague were...
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Injectable Gel Might Help Relieve Chronic Low-Back Pain Due to Degenerative Disc Disease
By Reuters Staff June 09, 2022 NEW YORK (Reuters Health) – An experimental hydrogel injected into spinal discs appears to relieve pain and improve function in patients with chronic low-back pain caused by degenerative disc disease (DDD), according to an early feasibility study. The hydrogel was successfully and safely injected into all targeted intervertebral discs and led...
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Immune system uses two-step verification to defend against HIV
SCRIPPS RESEARCH INSTITUTE IMAGE: FOR INNATE IMMUNE SYSTEM ACTIVATION AGAINST HIV-1, SCRIPPS RESEARCH SCIENTISTS HAVE FOUND THAT THE PROTEIN PQBP1’S RECOGNITION OF INCOMING HIV-1 PARTICLES (DEPICTED IN RED) IS REQUIRED FOR CGAS ACTIVATION, A PRODUCTION OF CGAMP (DEPICTED IN GREEN), IN HUMAN DENDRITIC CELLS. NUCLEI (DAPI) ARE DEPICTED IN BLUE. CREDIT: SCRIPPS RESEARCH LA JOLLA,...
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Antibiotic treatments may make us more susceptible to negative emotions
by Leiden University Schematic of the emotional dot-probe task. The task presents two faces simultaneously (one with an emotional expression and the other a neutral expression), followed by a probe in place of one of the faces. The reaction time to click the probe is taken as a measure of attention. In congruent trials, the...
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Carbon Monoxide-Loaded Foam as Inflammatory Disease Treatment
JULY 7TH, 2022 CONN HASTINGS GI, MATERIALS, MEDICINE Researchers at MIT have created a carbon monoxide-loaded foam intended for therapeutic use against inflammatory disease. While the gas is toxic if inhaled in large quantities, in small doses it has potent anti-inflammatory effects. However, delivering it to the gastrointestinal tract to treat inflammatory diseases, such as colitis,...
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Whole exome sequencing predicts whether patients respond to cancer immunotherapy
by New York University The steps of CIRCLE: 1) Combine immunotherapy whole-exome sequencing datasets. 2) Identify mutated genes and pathways. 3) Test candidate genes and pathways for response association. 4) Predictive framework for therapy response (determining Responder or Non-responder). Credit: Sanjana and Imieliński Labs Immunotherapies, such as immune checkpoint inhibitors, have transformed the treatment of advanced...
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Severe flu risk as immune cells swap with age
by Michael Keller, ETH Zurich AM and Mo-derived cells in influenza-infected mice. FeMo-reconstituted Csf2ra-/- and WT mice were infected with IAV (20 pfu PR8) as depicted in Fig. 2A. Representative gates and dot plots of BAL AM and BMo-Mac are shown on d10 and d21 p.i. Data are representative of at least 3 independent experiments with...
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Ways to Stay Linked in a Distance Relationship
If you are within a distance relationship, it can be challenging to stay connected. But if is made sure to prioritize your partner and communicate honestly, a long-distance relationship can work. Research suggests that thai girl for marriage long relationships are only as good in creating intimacy and great emotions since those who live close...
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Higher physical activity may lower risk of heart disease in adults with chronic kidney disease
NATIONAL KIDNEY FOUNDATION IMAGE: VISUAL ABSTRACT FOR “SELF-REPORTED PHYSICAL ACTIVITY AND CARDIOVASCULAR EVENTS IN ADULTS WITH CKD: FINDINGS FROM THE CRIC (CHRONIC RENAL INSUFFICIENCY COHORT) STUDY” BY JACOB W. BRUINIUS ET AL (AJKD, 2022) CREDIT: AJKD 2022 In this long-term study of 3,926 adults with chronic kidney disease (CKD) recently published in the American Journal...