by Chris Barncard, University of Wisconsin-Madison Outlined in green, this nucleus of a cancerous cell contains DNA in blue and red blobs marking the cell’s p53 protein binding with parts of the Atk cellular signaling pathway, a partnership that will prevent the cancerous cell from dying as it should and instead prolong its life and...
by University of Pittsburgh Credit: CC0 Public Domain While patients with diabetes on Medicare Advantage plans are more likely to receive preventive treatments, they were less likely to be prescribed newer, more expensive medications and were more likely to have higher blood pressure and worse blood glucose control than patients on Medicare Fee-For-Service plans, according...
by National Institutes of Health Sound reduces pain in mice by lowering the activity of neurons in the brain’s auditory cortex (green and magenta) that project to the thalamus. Credit: Wenjie Zhou An international team of scientists has identified the neural mechanisms through which sound blunts pain in mice. The findings, which could inform development...
by The University of Hong Kong Credit: Pixabay/CC0 Public Domain A joint research team from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) and City University of Hong Kong (CityU) has discovered that the electrical stimulation of the eye surface can alleviate depression-like symptoms and improve cognitive function in animal models. These...
By Edward ChenJuly 7, 2022 Reprints A patient with pills of Paxlovid. Six months after the emergency use authorization of Paxlovid for high-risk Covid patients, physicians say prescribing still isn’t clear-cut. ALEX WELSH/THE NEW YORK TIMES Six months after regulators issued an emergency use authorization for Paxlovid, physicians say they still have significant questions about prescribing guidelines...
Max Kozlov Surgeons at New York University transplanted pig kidneys into legally dead people on ventilators for the first time late last year.Credit: Joe Carrotta for NYU Langone Health In the months since physicians showed that it is possible to transplant pig organs into humans, researchers have been calling for US regulators to allow clinical...
By Aimee Molineux Reviewed by Emily Henderson, B.Sc. Johanson–Blizzard syndrome (JBS) is a rare autosomal recessive condition caused by homozygous and compound heterozygous mutations in the UBR1 gene. Until 2005, the genetic abnormality that caused the syndrome was unknown. Multisystem involvement and facial dysmorphic characteristics are hallmarks of this syndrome. Bilateral severe to profound sensorineural...
The study identifies gut bacterial strains that suppress inappropriate gut inflammation and debilitating inflammatory bowel disease (IBD) symptoms. IBD is a chronic condition characterized by relapsing gut inflammation believed to be caused by an abnormal gut bacterial composition which produces an immune response in genetically susceptible people resulting in severe symptoms. Researchers isolated bacteria found in the...
WILEY Measles is one of the most infectious airborne viruses worldwide. An inexpensive and effective vaccine is available, but Measles is common in developing countries and sporadic outbreaks also occur in developed countries, primarily due to non-vaccinated people. New research published in Advanced Functional Materials describes a novel point-of-care biosensing device capable of detecting measles virions in...
WILEY Gout occurs when urate crystals accumulate in the joints, and xanthine oxidase inhibitors such as febuxostat are a mainstay of therapy to help reduce blood urate levels in affected patients. A recent clinical trial published in Arthritis & Rheumatology has found that low doses of a less commonly used drug called benzbromarone may be a better...
