Month: <span>July 2022</span>

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Shapeshifting microrobots can brush and floss teeth
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Shapeshifting microrobots can brush and floss teeth

UNIVERSITY OF PENNSYLVANIA IMAGE: ARRANGED IN BRISTLE-LIKE STRUCTURES, A ROBOTIC MICROSWARM OF IRON OXIDE NANOPARTICLES DEVELOPED BY A TEAM FROM THE UNIVERSITY OF PENNSYLVANIA EFFECTIVELY CLEANED PLAQUE FROM TEETH. THE NANOPARTICLES HAVE BOTH MAGNETIC AND CATALYTIC PROPERTIES; CATALYZED HYDROGEN PEROXIDE PRODUCED FREE RADICALS THAT ELIMINATED TOOTH DECAY-CAUSING PATHOGENS AS WELL. CREDIT: IMAGE: MINJUN OH/PENN DENTAL...

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New research challenges long-held beliefs about limb regeneration

TEXAS A&M UNIVERSITY Ken Muneoka is no stranger to disrupting the field of regeneration; for example, in a 2019 ground-breaking publication in Nature, the Texas A&M University College of Veterinary Medicine & Biomedical Sciences (CVMBS) professor proved for the first time that joint regeneration in mammals was possible. Now, his team is again challenging other centuries-old beliefs about the...

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“Good evidence” that ADHD drugs might also treat Alzheimer’s disease

BMJ There is “good evidence” that drugs to treat attention deficit hyperactivity disorder (ADHD)might also successfully treat key aspects of Alzheimer’s disease, finds a pooled data analysis of the available research, published online in the Journal of Neurology Neurosurgery & Psychiatry. Clinical trials of noradrenergic drugs, which include antidepressants and medicines to treat high blood pressure...

How Omicron dodges the immune system
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How Omicron dodges the immune system

UNIVERSITÉ DE GENÈVE IMAGE: MERIEM BEKLIZ, FIRST AUTHOR, WITH A PLAQUE-REDUCTION NEUTRALIZATION ASSAY USED TO DETERMINE THE NEUTRALIZING CAPACITY OF ANTIBODIES. CREDIT: HUG-UNIGE The current wave of COVID-19 highlights a particularly high risk of reinfection by the Omicron variant of SARS-CoV-2. Why is this? A team from the Centre for Emerging Viral Diseases of the...

Researchers reveal the new function of TERC on PD-L1 inhibition
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Researchers reveal the new function of TERC on PD-L1 inhibition

SCIENCE CHINA PRESS IMAGE: TERC INHIBITS PD-L1 EXPRESSION AND AVOIDS CANCER IMMUNE ESCAPE CREDIT: ©SCIENCE CHINA PRESS TERC is a lncRNA with 451nt that functions as the template for telomerase during telomere lengthening. Several studies showed that TERC also functions as a lncRNA independent of telomerase, such as anti-apoptosis and regulates DNA damage response (Gazzaniga...

Stem cells reveal underpinnings of rare immune disease
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Stem cells reveal underpinnings of rare immune disease

KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY (KAUST) IMAGE: THE WILD TYPE (WT) MACROPHAGE (LEFT) AND THE WISKOTT-ALDRICH SYNDROME PROTEIN KNOCKOUT (WASP-KO) MACROPHAGE (RIGHT), AS CAPTURED BY A NANOLIVE MICROSCOPE. CREDIT: © 2022 KAUST. A new stem cell study by KAUST researchers helps to explain a rare genetic disease called Wiskott-Aldrich syndrome (WAS), yielding molecular...

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Pulse oximeters missed low oxygen levels in more Black veterans than White veterans

MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN Early in the COVID-19 pandemic, research from the University of Michigan uncovered inaccuracy in readings based on race when using pulse oximeters, finger-tip devices used to determine how much oxygen is present in the blood in patients in respiratory failure. This work was followed by other studies from around...

Study reveals how gastric cancer forms, suggests preventive treatment
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Study reveals how gastric cancer forms, suggests preventive treatment

by  Vanderbilt University Graphical abstract. Credit: Gastroenterology (2022). DOI: 10.1053/j.gastro.2022.06.021 A recently published study reveals new insights into how gastric cancer develops and suggests a preventive treatment. Eunyoung Choi, Ph.D., assistant professor of Surgery, and colleagues identified for the first time that Trop2+/CD133+/CD166+ dysplastic stem cellsare a key source of clonal evolution of dysplasia to multiple types of gastric cancer. Their investigation further...

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Most patients with appendicitis can be treated with antibiotics

UNIVERSITY OF CALIFORNIA – LOS ANGELES HEALTH SCIENCES FINDINGS Outpatient antibiotic management of selected patients with appendicitis is safe, allowing many patients to avoid surgery and hospitalization, and should be considered as part of shared decision-making between doctor and patient. Of 726 participants who were randomized to receive antibiotics, 46% were discharged from the emergency...