REGENSTRIEF INSTITUTE INDIANAPOLIS – Adults, especially older adults, may be in pain or depressed but not able to convey details of their symptoms and quality of life to their doctors for various reasons including cognitive impairment. A new study from Regenstrief Institute and Indiana University School of Medicine researchers investigates whether adult patients and their...
Month: <span>July 2022</span>
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In Krabbe disease, neurons may bring about their own destruction
by Public Library of Science University at Buffalo Dr. Daesung Shin (left) and a graduate student Jacob Favret (right) discuss neurodegeneration found in the neuron-specific Krabbe disease model. Credit: Daesung Shin (CC-BY 4.0, creativecommons.org/licenses/by/4.0/) The gene defect underlying Krabbe disease causes degeneration of neurons directly, independent of its effects on other cell types, according to a...
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New imaging technology less accurate than MRI at detecting prostate cancer, trial shows
by European Association of Urology Prostate cancer cells. Credit: NIH Image Gallery A team of researchers in Australia and New Zealand has found that MRI scans can detect prostate cancer more accurately than the newer, prostate-specific -PSMA PET/CT scanning technique. The findings are being presented today at the European Association of Urology’s annual congress (EAU22), in...
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Asthmatics may soon breathe easier thanks to new breakthrough
by Edith Cowan University Credit: Pixabay/CC0 Public Domain New research led by Edith Cowan University has made an important discovery that could lead to more effective treatments for the world’s 262 million asthma sufferers. A study led by Dr. Stacey Reinke (ECU) and Dr. Craig Wheelock (Karolinska Institute, Sweden) found severe asthmatics have a distinct biochemical...
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Vitamin D supplement ‘overdosing’ is possible and harmful, warn doctors
by British Medical Journal Credit: Pixabay/CC0 Public Domain ‘Overdosing’ on vitamin D supplements is both possible and harmful, warn doctors in the journal BMJ Case Reports after they treated a man who needed hospital admission for his excessive vitamin D intake. ‘Hypervitaminosis D’, as the condition is formerly known, is on the rise and linked to a...
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Researchers develop rapid COVID-19 test to identify variants in hours
by UT Southwestern Medical Center Jeffrey SoRelle, M.D. Credit: UT Southwestern Medical Center Last year, pathologist Jeffrey SoRelle, M.D., and colleagues developed CoVarScan, a rapid COVID-19 test that detects the signatures of eight hotspots on the SARS-CoV-2 virus. Now, after testing CoVarScan on more than 4,000 patient samples collected at UT Southwestern, the team reports in Clinical...
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New imaging technique allows researchers to see gene expression in brains of live mice in real time
by University of Minnesota A University of Minnesota Twin Cities-led team has developed a new technique for imaging mRNA molecules in the brains of living mice. By genetically modifying a mouse so that it produced mRNA labeled with green fluorescent proteins (shown above), the researchers were able to see when and where the mouse’s brain...
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New universal flu vaccine offers broad protection against influenza A virus infections, researchers find
by Georgia State University Rationale design of chimeric M2e-H3 stalk protein, purification, and confirmation. A Schematic of full-length HA gene of influenza A virus (A/Aichi/H3N2), and the selective domains as a vaccine target are numbered in amino acid (aa 37-61, 305-338, 1-117) residues. B M2e-H3 stalk vaccine construct with flexible and soluble linker sequences (AAAGGAA; GGGGS;...
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Hip flexors get weak when we sit too much—but simple stretches and strengthening exercises can leave you less stiff
by Andrew Lavender, The Conversation Credit: Shutterstock I am sure you’ve been told you should stand up and move away from your work stations or use a standing desk where possible. One of the major benefits of doing this is to activate and stretch the hip flexor area. But what are the hip flexors, and why...
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New research maps possible molecular origins of kidney disease
by University of Pennsylvania Credit: Pixabay/CC0 Public Domain After mapping the genetic underpinning of kidney function in 1.5 million people and about 60,000 kidney cells that are the microscopic mechanisms of gene regulation, researchers at the Perelman School of Medicine at the University of Pennsylvania found that more than 500 genes likely contribute to kidney...