UNIVERSITY OF CALIFORNIA – SANTA BARBARA IMAGE: A PAIR OF DNMT3A ENZYMES JOIN TWO AUXILIARY PROTEINS (GREEN) TO FORM A FOUR-PART COMPLEX THAT TRAVELS ALONG DNA ADDING CHEMICAL TAGS THAT TELL A CELL WHICH GENES TO EXPRESS. CREDIT: JONATHAN SANDOVAL ET AL. Chemotherapy sucks. The treatments generally have awful side effects, and it’s no secret...
Physical activity may have a stronger role than genes in longevity
UNIVERSITY OF CALIFORNIA – SAN DIEGO IMAGE: ALADDIN H. SHADYAB, PH.D., ASSISTANT PROFESSOR AT THE HERBERT WERTHEIM SCHOOL OF PUBLIC HEALTH AND HUMAN LONGEVITY SCIENCE AT UC SAN DIEGO CREDIT: UNIVERSITY OF CALIFORNIA SAN DIEGO Previous research has shown that low physical activity and greater time spent sitting are associated with a higher risk of...
Level of trust in doctor may influence patient’s brain responses to pain
UNIVERSITY OF MIAMI When doctors are seen as less trustworthy by their patients it can increase reported pain and pain-related brain activity, new research from the University of Miami suggests. In a study recently published in Cerebral Cortex and led by recent University of Miami Psychology Ph.D. graduate Steven R. Anderson, and Elizabeth Losin, assistant professor of psychology...
Developing a new treatment for common knee injury
by University of Cincinnati Credit: Pixabay/CC0 Public Domain Each year in the U.S., more than 500,000 people sustain tears in their meniscus, a piece of cartilage in the knee that cushions and stabilizes the joint. The tears often require invasive surgeries that frequently do not achieve the desired outcome. Researchers at the University of Cincinnati...
Pioneering stem-cell trials in Japan report promising early results
Smriti Mallapaty Induced pluripotent stem cells can turn into any type of cell. Credit: Steve Gschmeissner/Science Photo Library Some of the first trials to test whether reprogrammed stem cells can repair diseased organs have begun to report positive results. Research teams involved in the studies, all based in Japan, say they provide early hints that...
Their PMS mood swings were terrible. It was actually PMDD
By Natalie Bettendorf August 24, 2022 at 8:55 a.m. EDT In January 2021, Michele Petersen, then 25, began to not feel like herself. She had recently started dating her boyfriend long-distance, but suddenly she was feeling impatient and easily irritated when they talked. Little things he said or did would annoy her; she felt he...
Therapeutic drug renders cancer cell weapon harmless
UNIVERSITY OF BONN IMAGE: THEREBY INHIBITING THE IMMUNE SYSTEM (LEFT). CERITINIB STOPS THE FORMATION OF ADENOSINE. ATP ACCUMULATES AND ACTIVATES IMMUNE CELLS (RIGHT). CREDIT: FIGURE: LAURA SCHÄKEL/UNIVERSITY OF BONN – CREATED WITH BIORENDER.COM Many tumor cells mist themselves with a protective perfume that disables the immune system. But a drug already approved for other purposes can...
Children’s Hospital Colorado doctors pioneer non-invasive “string test” for sedation-free upper gastrointestinal monitoring
CHILDREN’S HOSPITAL COLORADO IMAGE: THE ENTEROTRACKER – COMMONLY REFERRED TO AS THE “STRING TEST” – IS BEING DEMONSTRATED HERE BY ONE OF ITS CREATORS, CHILDREN’S HOSPITAL COLORADO PEDIATRIC GASTROENTEROLOGIST GLENN FURUTA, M.D. CREDIT: CHILDREN’S HOSPITAL COLORADO Aurora, Colo. (Aug. 24, 2022) – Children’s Hospital Colorado (Children’s Colorado) has announced a new, care-changing test designed by its...
New study reveals that the yeast eps15-like endocytic protein Pan1p is a key player in endocytosis
TOKYO UNIVERSITY OF SCIENCE IMAGE: SCIENTISTS REVEAL KEY REGULATORY PROCESSES UNDERLYING THE MOLECULAR MECHANISMS OF ENDOCYTOSIS CREDIT: SCIENTIFIC ANIMATION A cell needs to constantly interact with its surrounding environment in a variety of ways to execute a plethora of biological functions. One such way is the uptake of extracellular materials, also known as endocytosis. In...
Technology developed at UH could advance treatment of lymphoma
UNIVERSITY OF HOUSTON IMAGE: NAVIN VARADARAJAN, UNIVERSITY OF HOUSTON M.D. ANDERSON PROFESSOR OF CHEMICAL AND BIOMOLECULAR ENGINEERING, STUDIED THE DYNAMIC INTERACTIONS BETWEEN T CELLS AND TUMOR CELLS TO DETERMINE WHICH PATIENTS ARE LIKELY TO RESPOND TO CAR T-CELL THERAPY TO TREAT LYMPHOMA. CREDIT: UNIVERSITY OF HOUSTON In the war against cancer, one of the most...