by Elin Bäckström, Uppsala University Brain from a mouse with CCM3 disease showing regions in the brain that lack oxygen (hypoxia, magenta) due to blood vessels (collagen IV, blue) that are occluded with coagulated blood (fibrin, green). Credit: Fabrizio Orsenigo och Maria Globisch In the condition known as cerebral cavernoma, lesions arise in a cluster...
Researchers closer to treating heart disease in diabetic patients
by University of Otago Graphical abstract. Credit: Molecular Therapy – Nucleic Acids (2022). DOI: 10.1016/j.omtn.2022.07.007 University of Otago researchers are closer to preventing immature death and improving the overall health of people with diabetes. More than 60% of people worldwide with type 2 diabetes die from some sort of heart disease. Associate Professor Rajesh Katare, of the Department...
Taking the pill may change your behavior, but exactly how is still uncertain
by Lindsie Arthur, Kathleen Casto and Khandis R Blake, The Conversation Credit: Reproductive Health Supplies Coalition / Unsplash The first hormonal contraceptive (the “pill”) was approved by the US Food and Drug Administration in 1960. Hormonal contraceptives have since become one of the most prescribed drugs in the world, used daily by more than 100 million...
Protein transformation drives cancer development
by Northwestern University Mitochondria. Credit: Wikipedia commons A change in function in a mitochondrial antioxidant protein increases stem cell gene expression that promotes the development of more aggressive cancerous cells, according to a recent Northwestern Medicine study published in Proceedings of the National Academy of Sciences. While the protein superoxide dismutase-2 (SOD2) has been known to...
Why does my breath smell bad, and what can I do about it?
by Arosha Weerakoon, The Conversation Brush your tongue as well as your teeth. Credit: Shutterstock Most of us can’t smell our own breath. If someone bravely informs you your breath smells, believe them, and do something about it. Or if you are worried you have bad breath, seek out a trusted opinion. Your breath can be...
Scientists unlock potential for a small cell lung cancer blood test
by Mike Addelman, University of Manchester Methylation score predicts survival in patients with SCLC. a, Kaplan–Meier curves showing OS of the 78 patients with SCLC stratified by high and low methylation score (derived from cfDNA samples and calculated as the average β-value across 4,061 genomic regions used by the tumor/healthy classifier, then dichotomized using the...
Bolstering the blood-CNS barrier could lead to new treatment approach for multiple sclerosis
by Jennifer Michalowski, University of Utah Health Sciences Graphical abstract. Credit: Neuron (2022). DOI: 10.1016/j.neuron.2022.07.015 Millions of people worldwide are living with multiple sclerosis (MS), a disease in which the immune system attacks cells in the central nervous system (CNS), causing unpredictable symptoms that can include tremors, weakness, vision problems, and fatigue. Treatments for MS aim to...
Why narcissists are more likely than others to believe in conspiracy theories
by Bob Yirka, Medical Xpress Components of narcissism proposed by Miller and colleagues and their links to conspiracy beliefs. Credit: Current Opinion in Psychology (2022). DOI: 10.1016/j.copsyc.2022.101386 A trio of researchers from the University of Kent, the Polish Academy of Sciences and the University of Cambridge believe they may have discovered why narcissists are more likely to...
Study points to new approach to clearing toxic waste from brain
by Washington University School of Medicine An extended form of the protein aquaporin 4 (red) lines the edges of tiny blood vessels in the brain. Cell nuclei are visible in blue. Researchers at Washington University School of Medicine in St. Louis have found a new druggable pathway that enhances the amount of long aquaporin 4...
Could patients draw blood at home?
Blood draws are essential, but this doesn’t make them anyone’s favourite pastime: they are time-consuming and involve needles. Is there a way to make it in a do-it-yourself (DIY) fashion? Can we collect blood samples at home? While this method will be far from omnipotent for the unforeseeable future, it might have its merits. The...