by Karl Guido, Universitaet Tübingen Graphical abstract. Credit: Circulation Research (2022). DOI: 10.1161/CIRCRESAHA.122.321109 A University of Tübingen team has discovered how malformations of the blood vessels can occur in mice—yielding information with possible ramifications for retinal disease The heart pumps blood through the vascular system, supplying cells with oxygen and energy. Smooth muscle cells in the vessels finely...
Month: <span>August 2022</span>
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Higher risk of blood clots in COVID-19 outpatients, largely reduced after vaccination
by University of Oxford Credit: Shutterstock Researchers at NDORMS have studied the association between ambulatory COVID-19 and short-term risk of venal thrombosis and the clinical and genetic risk factors predisposing them to developing post–COVID-19 thrombosis. Ambulatory COVID-19 patients (those diagnosed as outpatients) face an elevated risk of venal thrombosis (blood clot in a vein) than...
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Discovery suppresses progression of kidney fibrosis
by Virginia Tech Webster Santos, the Cliff and Agnes Lilly Faculty Fellow in the Virginia Tech College of Science and a professor in the Department of Chemistry, in his lab at Davidson Hall. Credit: Greg Atkins, Virginia Tech Webster Santos is determined to find a way to halt kidney fibrosis, a condition caused by persistent...
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Researchers discover ‘weak spot’ across major COVID-19 variants
by University of British Columbia Cryo-electron microscopy reveals how the VH Ab6 antibody fragment (red) attaches to the vulnerable site on the SARS-CoV-2 spike protein (gray) to block the virus from binding with the human ACE2 cell receptor (blue). Credit: Dr. Sriram Subramaniam, UBC Researchers at the University of British Columbia have discovered a key vulnerability...
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Lupus Pill Shows Promise in Mice; Clinical Trial Underway
Summary: Afimetoran, a newly developed pill to treat lupus, not only prevents lupus-like symptoms in mice, it also reverses signs of organ damage caused by the disease and prevents death. The medication is now undergoing phase 2 clinical trials to assess its effectiveness in lupus patients. Source: American Chemical Society Lupus is an autoimmune disease that attacks...
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Medicine known for decades and costing 57 cents a day can restore lost hair, doctors find – but only works in most patients when it is taken as a pill rather than an ointment
By LUKE ANDREWS HEALTH REPORTER FOR DAILYMAIL.COM PUBLISHED: 18:06 EDT, 19 August 2022 | UPDATED: 18:14 EDT, 19 August 2022 A medicine doctors have known can cure hair loss for decades could be more effective that previously believed if the way its taken – via pill instead of via an ointment – is changed. Minoxidil — sold under the brand...
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Digital Therapy May ‘Rewire’ the Brain to Improve Tinnitus
Kelli Whitlock Burton August 18, 2022 A cell phone app that combines white noise, active game-based therapy, and counseling could help “rewire” the brain to provide relief from tinnitus symptoms, new research suggests. In a randomized controlled trial, results at 12 weeks showed patients with tinnitus reported clinically meaningful reductions in ratings of annoyance, inability to ignore,...
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Out-of-pocket cost of naloxone may keep many uninsured from using life-saving treatment
by RAND Corporation Credit: Unsplash/CC0 Public Domain The cost of buying the opioid antidote naloxone is out of reach for many uninsured Americans, a hurdle that may keep the treatment from saving more people who overdose on opioids, according to a new RAND Corporation study. While laws making it easier to prescribe and obtain naloxone...
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Neuron membrane lipid may contribute to Alzheimer’s development, progression
by Zach Sweger, Pennsylvania State University Graphical abstract. Credit: ACS Chemical Neuroscience (2022). DOI: 10.1021/acschemneuro.2c00221 A lipid found in the membranes of neurons may play a fundamental role in the development and progression of Alzheimer’s disease, according to a study by Penn State College of Medicine researchers. Their findings, published in ACS Chemical Neuroscience, provide possibilities for new...
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Pancreatic cancer clinical trial to test new approach to treatment
A clinical trial into pancreatic cancer treatment will explore findings from the Garvan Institute of Medical Research that suggest a new targeted treatment can make the tumours more susceptible to chemotherapy and improve patient survival rates. A blood test. Image credit: U.S. Air Force photo by Staff Sgt. Teresa J. Cleveland, Public Domain via Health.mil The new trial...