RIKEN IMAGE: THE CONDITION OF MICE WITH COLITIS IMPROVED AFTER TREATMENT WITH DAIKENCHUTO, A MEDICINE MADE FROM GINGER, GINSENG, AND JAPANESE PEPPER. ANALYSIS SHOWED THAT THIS WAS BECAUSE IT PREVENTS THE LOSS OF KEY BACTERIA IN THE GUT AND FACILITATES THE ACTIVITY OF INNATE IMMUNE CELLS IN THE GUT CALLED ILC3S. CREDIT: RIKEN Zhengzheng Shi...
CEDARS-SINAI MEDICAL CENTER The majority of people who were likely infected with the Omicron variant of SARS-CoV-2, the virus that causes COVID-19, didn’t know they had the virus, according to a new study from Cedars-Sinai investigators. The findings are published in JAMA Network Open. “More than one in every two people who were infected with Omicron...
by H. Lee Moffitt Cancer Center & Research Institute Credit: Min Yu (Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC),USC Norris Comprehensive Cancer Center Cells in the surrounding tumor microenvironment have a significant impact on cancer growth, survival and responses to therapy. Cancer-associated fibroblasts in the tumor environment have typically...
by Kevin McCullough, Northwestern University Loss of IL-6 rescues multi-organ leukemia infiltrations in DKO mice. (A) Microarray gene expression data of bone marrow CD34+ cells from 47 MDS patients. Housekeeping genes GAPDH and ACTB were plotted to demonstrate the modest raw intensity without normalization. TNNT2 and CD34 were plotted as negative and positive controls, respectively. Data...
by University of Geneva When diabetes starts to develop but no symptoms are yet detectable, part of the beta cells of the pancreas (in green) disappear (right image) compared to a healthy individual (left image). This previously undetectable decrease could be identified by measuring the level of 1,5-anhydroglucitol in the blood. Credit: UNIGE – Laboratory...
by Stephanie Winn, UC Davis Credit: Unsplash/CC0 Public Domain A new study has found that a current cancer diagnosis posed a significant risk for severe outcomes during the first two years of the COVID-19 pandemic, including ICU admission and death. UC Davis Comprehensive Cancer Center researchers took part in the study, which was published this...
by University of Surrey Credit: Unsplash/CC0 Public Domain Researchers have identified what they believe to be robust metabolic markers of COVID, a discovery that could lead to better understanding and treatments for people that suffer from symptoms of the disease months after diagnosis. Scientists from the University of Surrey collected blood samples of hospital patients and found that COVID-19...
by Jeff Hansen, University of Alabama at Birmingham Credit: Priyanka Gupta et al, Cell Reports (2022). DOI: 10.1016/j.celrep.2022.111218 Researchers have deciphered a signaling cascade through which inborn errors in metabolism provoke deadly neuroendocrine tumors in the adrenal glands. This discovery explains how impaired metabolism due to mutations in a key enzyme called succinate dehydrogenase B disables a...
by University of Helsinki Cumulative incidence plots for first event of myocardial infarction in FinnGenR6. Red line represents carriers (homo- or heterozygous) for either rs534125149 or rs201988637 (n = 17,838), and blue line represent non-carriers (n = 242,567). Hazard ratio and p-value are from cox-proportional hazards model. Dashed lines represent 95% confidence intervals. Credit: Communications Biology (2022). DOI: 10.1038/s42003-022-03552-0 A variant...
by Wellcome Trust Sanger Institute Credit: Pixabay/CC0 Public Domain A pioneering genomic surveillance study has provided the clearest picture yet of the arms race between Streptococcus pneumoniae, the bacterium responsible for a range of illnesses such as pneumonia and meningitis, and the vaccines designed to protect against the most dominant types. A strain called GPSC10 was...
