by University of California, Los Angeles Credit: Pixabay/CC0 Public Domain Primary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the United States each year. The high mortality rates can be attributed in part to the fact that a significant portion of the patients are detected at a late...
New insights into retinal neurons
by Will Doss, Northwestern University Left: Retinal ganglion cell recorded both at its cell body (soma) and at its axon, which sends spikes to the brain. Right: Electrical trace from the soma and axon of the cell on the left. Large somatic spikes are transmitted down the axon. Small spikes are not. Credit: Northwestern University...
Sleep Disorders an Early Dementia ‘Warning Sign’?
Pauline Anderson August 03, 2022 Sleep disorders are associated with a 17% increased risk for dementia, results from a large registry-based study show. “From our research, we can’t exclude a diagnosis of a sleep disorder in many cases being a warning sign for dementia,” study investigator Gunhild Waldemar, MD, professor of clinical neurology, Faculty of Health and...
Hyaluranic acid, a naturally occurring compound, awakens stem cells to repair damaged muscle
by The Ottawa Hospital When a muscle fiber is damaged, stem cells (in pink) start producing and coating themselves with hyaluronic acid (pale green outline). Once the coating gets thick enough, it causes the muscle stem cells to wake up. Credit: Dr. Kiran Nakka A new study published in the journal Science reveals a unique...
U.S. declares monkeypox outbreak a public health emergency
By Helen Branswell Aug. 4, 2022 Reprints Colorized transmission electron micrograph of monkeypox virus particles (teal) cultivated and purified from cell culture.NIAID The Biden administration declared the ongoing monkeypox outbreak a public health emergency on Thursday, a move that comes amid growing case counts and a groundswell of criticism over the way the administration has...
Designing an app to diagnose ALS
Interview conducted by Emily Henderson, B.Sc. Aug 4 2022 Thought LeadersDr. Jordan GreenDirector of the Speech and Feeding Disorders LabMGH Institute of Health Professions In this interview, we speak to Dr. Jordan Green from the MGH Institute about his latest research partnership with Modality.AI which investigated whether an app could be used to effectively diagnose...
Gene Therapy Approach Shows Promise in Treating ALS
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the progressive loss of motor neurons in the brain and spinal cord responsible for voluntary movements and muscle control. In a new study, published in the journal Theranostics, researchers at University of California San Diego School of Medicine report that a gene therapy approach, developed at UC...
Lumen: World’s First Device and App for Real-time Metabolic Feedback
AUGUST 3RD, 2022 ALICE FERNG EXCLUSIVE, MEDICINE Lumen is the first device and app available to anyone that provides real-time feedback on whether you’re burning carbohydrates or fats. These measurements are usually only made for athletes or patients through special testing centers, hospitals, or clinics, but with Lumen they are now available to everyone, anywhere. Nutrition...
Engineering the microbiome to potentially cure disease
UNIVERSITY OF CALIFORNIA – SAN DIEGO IMAGE: AN ARTIST’S RENDERING OF THE CONCEPT OF RE-ENGINEERED NATIVE BACTERIA THAT SERVE AS CHASSIS TO INTRODUCE THERAPEUTICS INTO THE GUT MICROBIOME TO TREAT OR CURE DISEASE. CREDIT: THOM LEACH, AMOEBA STUDIOS Residing within the human gut are trillions of bacteria and other microorganisms that can impact a variety...
A new therapeutic drug for Alzheimer’s disease without inflammatory side effects
THE KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KAIST) IMAGE: SCHEMATIC OF A CHIMERIC GAS6 FUSION PROTEIN. A SINGLE CHAIN VARIABLE FRAGMENT (SCFV) OF AN AMYLOID Β (AΒ)-TARGETING MONOCLONAL ANTIBODY IS FUSED WITH A TRUNCATED RECEPTOR BINDING DOMAIN OF GAS6, A BRIDGING MOLECULE FOR THE CLEARANCE OF DEAD CELLS VIA TAM (TYRO3, AXL, AND MERTK)...