THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE In a potential game changer for patients with type 2 diabetes, a team of researchers at the Diabetes, Obesity, and Metabolism Institute (DOMI) at the Icahn School of Medicine at Mount Sinai has identified a therapeutic target for the preservation and regeneration of beta cells...
Month: <span>August 2022</span>
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Study provides insight into how the intestine repairs damaged tissue
CEDARS-SINAI MEDICAL CENTER Investigators at Cedars-Sinai and the University of California, San Francisco (UCSF) have identified a component in the intestine that plays a critical role in repairing damaged tissue. Scientists found that endothelial cells in the lymphatic vessels produce molecules that are essential for the maintenance and regulation of stem cells and tissues in the intestine....
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Potential treatment identified for bladder cancers that are ARID1A-deficient
UNIVERSITY OF ALABAMA AT BIRMINGHAM IMAGE: JAMES “JED” FERGUSON III CREDIT: UAB BIRMINGHAM, Ala. – Metastatic bladder cancer is generally incurable, so new therapies are an urgent need. Researchers at the University of Alabama at Birmingham now report a potential treatment for a quarter of bladder cancers. Their discovery, published in the journal JCI Insight, comes from...
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Sponge-like electrodes inspired by sugar cubes could improve medical monitoring
AMERICAN CHEMICAL SOCIETY IMAGE: SPONGE ELECTRODES, SEEN HERE IN A VARIETY OF THICKNESSES, USE SUGAR CUBES AS TEMPLATES. CREDIT: ADAPTED FROM ACS NANO 2022, DOI: 10.1021/ACSNANO.2C04962 To monitor heart rhythms and muscle function, doctors often attach electrodes to a patient’s skin, detecting the electrical signals that lie beneath. These impulses are vital to the early...
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A new low-calorie sweetener could also improve gut health, study shows
AMERICAN CHEMICAL SOCIETY From the wide variety of sodas, candies and baked goods that are sold worldwide, it’s clear that people love their sweet treats. But consuming too much white table sugar or artificial sweetener can lead to health issues. In the search for a better sweetener, researchers in ACS’ Journal of Agricultural and Food Chemistry now...
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Earbuds may soon detect ear infections, other ailments
by Cory Nealon, University at Buffalo An illustration showing how EarHealth works. Credit: University at Buffalo New University at Buffalo-led research shows how earbuds may soon be able to detect common ear infections and other ailments. A study published in June by the Association for Computing Machinery (ACM) describes what the research team is calling EarHealth. The...
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Stopping moles from turning into the deadliest type of skin cancer
by Boston University BRAFV600E activates the Hippo tumor-suppressor pathway. a Representative immunoblot (IB) of dox-inducible BRAFV600E Mel-ST cells cultured ± dox for 24 h. b IB of two different dox-inducible BRAFV600E Mel-ST clones cultured ± dox for 24 h (n ≥ 4 independent experiments, graph shows mean relative intensity ± SEM, two-tailed unpaired t test). c Left, IB of two dox-inducible BRAFV600E Mel-ST clones cultured...
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Scientists engineer probiotic to prevent infection of large intestine
by National University of Singapore Schematic of the engineered probiotics against CDI. Probiotics were engineered to restore intestinal bile salt metabolism in response to antibiotic-induced microbiome dysbiosis in order to inhibit the germination and growth of C. difficile. Credit: Nature Communications (2022). DOI: 10.1038/s41467-022-31334-z Scientists from the Yong Loo Lin School of Medicine, National University of Singapore...
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Bacteria-busting proteins offer potential for smarter drugs
by Australian National University PhD scholar Shouya Feng (left) and Professor Si Ming Man. Credit: Dr Chinh Ngo/ANU A specific group of bacteria-killing proteins inside the immune system could hold the key to developing smarter and more effective drugs capable of eliminating certain infectious diseases including meningitis, pneumonia and sepsis, according to scientists from The...
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Passive exercise offers same brain health benefits as active movements, study finds
by Kim McCready, University of Western Ontario Cycle pedals mechanically being pushed was used to determine effects of passive exercise on cognition. Credit: University of Western Ontario A new study by kinesiology graduate students from Western has found passive exercise leads to increased cerebral blood flow and improved executive function, providing the same cognitive benefits...