CENTER FOR GENOMIC REGULATION Researchers at the Centre for Genomic Regulation (CRG) have identified several proteins involved in the progression of melanoma, the deadliest form of skin cancer. One of the proteins – PDIA6 – was found to be particularly important for driving malignancy. Experiments with mice showed that melanoma cells with reduced levels of...
Month: <span>August 2022</span>
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More women turning to medical cannabis for relief of menopause symptoms
THE NORTH AMERICAN MENOPAUSE SOCIETY (NAMS) CLEVELAND, Ohio (August 3, 2022)—The legalization of medical cannabis has led to its use in treating a growing number of health problems. A new study suggests that it is becoming more common for women to use medical cannabis for menopause-related symptoms. Perimenopausal women, who report significantly worse menopause symptoms...
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Researchers call for new studies to learn how our brains change when we’re awake after midnight
by Massachusetts General Hospital Credit: CC0 Public Domain If you’ve ever stayed up late angrily commenting on Twitter posts, eating a whole pint of ice cream out of the container, finishing another bottle of wine, or just feeling miserable, you might identify with the Mind After Midnight hypothesis. The hypothesis, which was detailed in a...
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New research could lead to a simple blood test for brain tumors
by University of Bristol Concept of how mathematical modeling may be used in the development and deployment of blood-based biomarkers for brain tumors. This figure summarizes the role mathematical modeling could play in blood-based liquid biopsy development and implementation. Credit: Dr Johanna Blee, University of Bristol. University of Bristol research could lead to better detection...
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Small daily portion of Jarlsberg cheese may help to stave off bone thinning
by British Medical Journal Credit: Unsplash/CC0 Public Domain A small (57 g) daily portion of Jarlsberg cheese may help to stave off bone thinning (osteopenia/osteoporosis) without boosting harmful low density cholesterol, suggest the results of a small comparative clinical trial, published in the open access journal BMJ Nutrition Prevention & Health. The effects seem to be...
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Are persistent infections of novel coronavirus the cause of sequelae in infected hosts?
by Toyohashi University of Technology “Average symptoms” shows the results derived from a baseline model when applying a mathematical model to clinical data. Results show “Increased severity” based on “deficient” immunity bearing in mind age-related risk factors. Conversely, the results show a “Complete cure” based on “robust” immunity. Aside from “Increased severity”, even with “Average...
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Ditching the toothbrush for whiter teeth, fewer cavities
by American Chemical Society A new hydrogel treatment breaks apart cavity-forming biofilms and whitens teeth without damaging enamel. Credit: American Chemical Society The first thing people notice when they meet you is your smile. To be more confident when giving wide-mouthed, eye-crinkling smiles, people want healthy, pearly white teeth. But toothpastes only remove surface stains,...
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Novel drug shows promising efficacy for patients with multiple myeloma
by Jenny Owen, Emory University Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAID Results of an international clinical trial co-led by researchers at Winship Cancer Institute at Emory University show potential for a novel drug to benefit patients with multiple...
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Uncovering the links between diet, gut health and immunity
by University of Sydney Model of high protein diet in the induction of sIgA response. High protein diet feeding promotes succinate production by the gut microbiota. High levels of luminal succinate induce gut bacterial cellular stress and reactive oxygen species (ROS) production, which promote vesiculation and increased production of microbiota-derived extracellular vesicles. Microbiota-derived extracellular vesicles...
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Gaining insights into spastic paraplegia
by Friedrich–Alexander University Erlangen–Nurnberg Credit: CC0 Public Domain Rare diseases, as the name indicates, only affect a small part of the population. However, for those affected they are particularly challenging, often especially because research into such rare diseases tends to be less of a priority. One of these diseases is hereditary spastic paraplegia (HSP), a...