by University of Texas Health Science Center at Houston Credit: Pixabay/CC0 Public Domain Targeting a specific enzyme in the muscle could help cancer patients preserve muscle mass and potentially prolong their survival, according to research from UTHealth Houston. A study led by Yi-Ping Li, Ph.D., professor in the Department of Integrative Biology and Pharmacology with...
Epigenetic changes linked to Parkinson’s disease differ in men and women
by Rutgers University Credit: Pixabay/CC0 Public Domain The epigenetic changes linked to Parkinson’s disease—a nervous system disorder that afflicts nearly 1 million Americans—are different in men and women, according to a new Rutgers study published in npj Parkinson’s Disease. In a postmortem analysis of brain neurons, researchers compared samples from 50 people who died with Parkinson’s...
Research team develops novel strategy to suppress prostate cancer growth
by Aaron Nieto, Baylor College of Medicine Prostate cancer cells. Credit: NIH Image Gallery Finding valuable therapeutic interventions for prostate cancer has long guided the research of Dr. Feng Yang’s lab at Baylor College of Medicine. In a study published in the Proceedings of the National Academy of Sciences, Yang’s team took a close look into...
Specific memories can be erased while you sleep — using simple ‘sound cue’ method
OCTOBER 18, 2022 by John Anderer HESLINGTON, United Kingdom — The past often serves to motivate and push us forward, but bad memories also have a way of holding us back. Traumatic, sad, or just downright embarrassing memories tend to persist in our minds and bubble to the surface at inopportune moments. Now, researchers from the...
New islet transplant method leads to insulin independence
by Perelman School of Medicine at the University of Pennsylvania A pancreatic islet from a mouse in a typical position, close to a blood vessel; insulin in red, nuclei in blue. Credit: Generated in the Solimena lab, Paul Langerhans Institute Dresden More than half of the most seriously affected type 1 diabetes patients achieved years...
Cancer-seeking molecular delivery system could boost immunotherapy drug, research finds
by University of Rhode Island Credit: Unsplash/CC0 Public Domain Researchers from the University of Rhode Island and Yale University have demonstrated a promising new approach to delivering immunotherapy agents to fight cancer. The approach involves tethering an immunotherapy agent called a STING agonist to an acid-seeking molecule called pHLIP (pH-low insertion peptide). The pHLIP molecules...
Deep learning tool identifies bacteria in micrographs
Omnipose, a deep learning software, is helping to solve the challenge of identifying varied and miniscule bacteria in microscopy images. It has gone beyond this initial goal to identify several other types of tiny objects in micrographs. The UW Medicine microbiology lab of Joseph Mougous and the University of Washington physics and bioengineering lab of Paul A. Wiggins tested the tool....
Study finds less expensive noninvasive test is an effective alternative for colorectal cancer screening
by American College of Surgeons Non-invasive, less expensive test is effective in early-stage colorectal cancer screening. Credit: American College of Surgeons Commercially available noninvasive screening tests for colorectal cancer—a fecal immunochemical test (FIT) and the multi-target stool DNAtest (mt-sDNA; or Cologuard®)—are equally effective for screening patients with early-stage colorectal cancer. However, a FIT costs about...
Zinc enhances albumin’s protective role against Parkinson’s disease
by King Abdullah University of Science and Technology Fig. 1. Fibrillization kinetics of AS under pH 7.4, low and high ionic strength in the presence and absence of Zn2+ and/or defatted human serum albumin (DE-HSA). (A) The nucleation dependent polymerization reaction of amyloid fibril formation causes a sigmoidal growth curve with nucleation, elongation, and saturation phases. (B)...
Arthritis drug boosts fat-signaling and counters diabetes in obese mice
By Nick Lavars October 17, 2022 An approved arthritis drug has shown promise in tackling diabetes and obesity in early mouse studies Depositphotos Scientists studying the activity of a drug used to treat rheumatoid arthritis have discovered it has some surprising functions, some of which may be useful when it comes to countering diabetes. The...