TOKYO MEDICAL AND DENTAL UNIVERSITY IMAGE: TAKAHASHI ET AL. SHOW THAT TGF-Β GENERATES A POPULATION OF CANCER CELLS UNDER CELL CYCLE ARREST IN G1 PHASE WITH HIGH MOTILITY BY INDUCING UNIQUE SLUG/HMGA2-INDEPENDENT EPITHELIAL-MESENCHYMAL TRANSITION (EMT). THIS LEADS TO TUMOR PROGRESSION AND POOR PROGNOSIS FOR PATIENTS WITH HEAD AND NECK CANCER. CREDIT: DEPARTMENT OF BIOCHEMISTRY, TMDU...
5 questions to ask before sharing health stories on social media
by Thor Christensen, American Heart Association News When it comes to posting health information on social media, beware before you share. Experts say that’s an essential step in battling medical misinformation, an escalating problem as more people turn to social media for news, knowledge and advice about all things health-related. In the wake of rampant false...
Some screen time better than none during children’s concussion recovery
by University of British Columbia Credit: Unsplash/CC0 Public Domain Too much screen time can slow children’s recovery from concussions, but new research from UBC and the University of Calgary suggests that banning screen time is not the answer. The researchers looked for links between the self-reported screen time of more than 700 children aged 8-16...
Nanotechnology, messenger RNA combined in possible new ‘universal’ COVID-19 treatment
by Steve Lundeberg, Oregon State University Depiction of mRNA therapy. Credit: OSU College of Pharmacy A study led by an Oregon State University pharmaceutical sciences researcher has produced a proof of principle for a new “universal” means of treating COVID-19. Gaurav Sahay and collaborators at OSU and the Texas Biomedical Research Institute demonstrated in a...
New way to prevent heart complications in children with Kawasaki disease
by Walter and Eliza Hall Institute of Medical Research Coronary artery sections showing differences between no heart disease (left) and the effect of acute Kawasaki disease (right). Credit: WEHI Researchers have identified a new way to treat young children with Kawasaki disease (KD) to prevent life-threatening coronary artery damage and heart attacks. The WEHI-led study...
In sub-Saharan Africa and South Asia, young children dying at greater-than-expected rates
by Michele W. Berger, University of Pennsylvania Clustering of categories of age patterns of under-5 mortality by region, from the first collected DHS in a given country (average year of collection 1993; A) to the last collected DHS in a given country (average year of collection 2014; B) For countries with only one survey, the...
Nicotine dose in a single cigarette blocks estrogen production in women’s brains
by European College of Neuropsychopharmacology Aromatase (estrogen synthetase) detected in the thalamus (red spot). Credit: Jana Immenschuh A dose of nicotine, equivalent to that found in a single cigarette blocks estrogen production in women’s brains. This may explain several behavioral differences in women who smoke, including why they are more resistant than men to quitting...
Increased mitochondria and lipid turnover reduces risk for liver cancer
by University of Chicago Medical Center Loss of BNIP3 promotes HCC initiation and tumor growth. (A) Representative images of HCC tumors forming in the liver of Bnip3+/+ and bnip3−/− mice at 24 and 40 weeks of age following DEN injection. Scale bars, 12.7 mm. (B) Graph of tumor number forming in the liver of Bnip3+/+ (red) and bnip3−/− (blue)...
Cardiovascular disease risks the same in both sexes
by University of Gothenburg Credit: Pixabay/CC0 Public Domain For men and women, the risk factors for cardiovascular disease are largely the same, an extensive global study involving University of Gothenburg researchers shows. The study, now published in The Lancet, includes participants in both high-income and medium- and low-income countries. Cardiovascular disease is more widespread in the latter....
Study identifies new gene that drives colon cancer
by The Mount Sinai Hospital Recurrently dysregulated super-enhancers in CRC patients. a Study overview. Figure adapted from SMART Servier Medical Art, reproduced with permission, licensed under a Creative Commons Attribution 3.0 unported license. b PCA of H3K27ac signal at 2026 SEs in CRC (n = 15 independent tissue samples), normal mucosa (n = 15), crypts (n = 4), and FAP adenomas (n = 2). c, d GSEA between SE proximal...