The compound, designated EBC-46 and technically called tigilanol tiglate, works by promoting a localized immune response against tumors. The response breaks apart the tumor’s blood vessels and ultimately kills its cancerous cells. EBC-46 recently entered into human clinical trials following its extremely high success rate in treating a kind of cancer in dogs. Given its complex...
Early deprivation continues to affect brain development well into adolescence, researchers find
by University of North Carolina at Chapel Hill Differences in longitudinal change in gray matter structure by group. (A) Regions with increased thinning between 9 and 16 years of age for children randomly assigned to foster care relative to those in care as usual. (B) Regions with accelerated thinning for children randomly assigned to foster...
Scientists identify link between mitochondria and pancreatic cancer risk
by The Wistar Institute Differential expression of a Mic60-low gene signature in cancer. Credit: PLOS ONE (2022). DOI: 10.1371/journal.pone.0273520 The mitochondria is a key energy-producing component of the human cell that plays an important role in cancer cell metabolism. In a research paper published in PLOS ONE, Dario C. Altieri, M.D., president and chief executive officer, director of...
Research sheds new light on long COVID conditions
by Mid-Atlantic Permanente Medical Group Credit: Unsplash/CC0 Public Domain Most people who get COVID-19 recover within a few weeks. But some people—even those who had mild versions of the disease—have symptoms that last weeks or months after an initial COVID infection. These ongoing health problems, called post-COVID conditions (PCC), post-COVID-19 syndrome, long COVID-19, and post-acute...
New device for early detection of gum disease
by University of Birmingham Change in area under the curve (AUC) for all combinations of validated analytes for differentiating between health or gingivitis and periodontitis (HG vs. P), health and gingivitis (H vs. G), and mild and advanced periodontitis (MP vs. AP). Data are represented as truncated violin plots; solid lines represent median and dashed...
Night sweats versus hot flashes
by The North American Menopause Society Credit: Pixabay/CC0 Public Domain What’s worse—night sweats or hot flashes as they relate to depression and stress? Although both can have a significant effect on a woman’s quality of life, a new study out of the University of Massachusetts suggests that night sweats might actually be more stressful. Study...
What you eat could contribute to your menstrual cramps
by The North American Menopause Society Credit: CC0 Public Domain Despite the fact that menstrual pain (dysmenorrhea) is the leading cause of school absences for adolescent girls, few girls seek treatment. An analysis of relevant studies suggests that diet may be a key contributor, specifically diets high in meat, oil, sugar, salt, and coffee, which...
Manual cleaning of medical instruments exposes staff and surrounding environment to potentially contaminated fluids
by Association for Professionals in Infection Control Credit: Pixabay/CC0 Public Domain A new study published today in the American Journal of Infection Control (AJIC) shows that manual cleaning of reusable medical instruments generates substantial splash more than seven feet from the source. The findings reinforce the importance of engineering controls and appropriate use of personal protective equipment...
Tips for treating the flu at home
by Angela Nelson, Tufts University About 30 million Americans will get the flu this season, but fortunately, most of those cases can be treated at home. Credit: Photoroyalty / Shutterstock It’s flu season, during which approximately 30 million Americans will get the flu, according to the Centers for Disease Control and Prevention. Fortunately, most of...
Symptoms, quality of life important to guide treatment for peripheral artery disease (PAD)
by American Heart Association Credit: Pixabay/CC0 Public Domain For the approximately 8.5 million people in the U.S. living with peripheral artery disease (PAD—pronounced P-A-D), which is narrowed or clogged arteries in the legs, treatment decisions and criteria for success should be led by their symptoms and self-reported quality of life, according to a new American...