by D’Or Institute for Research and Education In green, it shows the presence of 5-LOX. In red, MAP2 (microtubule-associated protein 2, essential for the structure of neuronal cells). In blue, the nuclei of these cells. Credit: The D’Or Institute for Research and Education (IDOR) Researchers from the D’Or Institute for Research and Education (IDOR) have...
Newly identified cell population could improve targeting of relevant macrophage populations in neurodegeneration
by Agency for Science, Technology and Research (A*STAR), Singapore The DAM population corresponds to a fetal-like reprogramming similar to Youth-Associated Microglia while DIMs appear during aging and increase in neurodegenerative diseases. Credit: A*STAR’s Singapore Immunology Network (SIgN) A research study published in Immunity has found that the previously identified disease-associated microglia (DAM) population detected in murine Alzheimer’s...
Are midlife women doomed to gain weight?
by The North American Menopause Society Credit: Pixabay/CC0 Public Domain Weight gain is a common complaint of midlife women, with more than two-thirds of midlife US women being over the ideal weight threshold. Aging-related metabolic changes promote weight gain in both sexes, but women face additional challenges because of menopause. A presentation at The North...
Hormone therapy may help prevent shoulder pain and loss of motion in menopausal women
by The North American Menopause Society Credit: Unsplash/CC0 Public Domain Women aged 40 to 60 years are most affected by adhesive capsulitis, a painful orthopedic disorder characterized by sudden shoulder pain and loss of range of motion. There has been limited research around the disorder’s predilection for perimenopausal women, but a new study found that...
Old drugs offer new ways of treating bowel cancer
by University of Auckland Credit: CC0 Public Domain Old medicines, combined in new ways, are showing promise for treating bowel cancer, a group of University of Auckland researchers has found. “While there have been advances in treatments for this disease in recent years, the development of new medicines is expensive and time-consuming,” lead researcher Professor Peter Shepherd...
A new way lactic acid can reduce a woman’s risk of getting an STI
by Burnet Institute Higher relative abundance of bacterial LDH in women with a Lactobacillus-dominated microbiome. The vaginal microbiome composition of 113 young women from Cape Town, South Africa, was determined using liquid chromatography-tandem mass spectrometry, and participants were classified as being bacterial vaginosis (BV) negative, positive, or intermediate (Int) using Nugent-BV criteria. Proteins were identified...
Study explores links between people taking multiple medications and dementia diagnosis
by University of Plymouth Credit: CC0 Public Domain People with dementia are likely to have taken more than three medications for other health conditions in the five years directly before their diagnosis, according to new research. The study is the first to provide an in-depth exploration of the links between evolving polypharmacy—which involves a patient...
Are smartwatch health apps to detect atrial fibrillation smart enough?
by Elsevier Example of false positive (failure to diagnose a normal ECG in patient without AF) electrocardiograms (ECGs) caused by occurrence of premature complexes or bradycardia and false negative (failure to detect AF in a patient with AF) ECGs caused by broad QRS complexes and ventricular pacing. Credit: Canadian Journal of Cardiology (2022). DOI: 10.1016/j.cjca.2022.08.222 Extended cardiac...
The role of the clinician-data-scientist in health care
by Health Data Science Credit: Pixabay/CC0 Public Domain Health care is constantly changing, as big data analytics and advanced technologies such as artificial intelligence are now being applied in the health care field. These high-tech changes hold the potential to transform patient care. In response to these changes, an international team of scientists has published...
Powerful enzyme that tamps down inflammation holds promise for protecting the eyes in diabetes, premature birth
by Medical College of Georgia at Augusta University Drs. Ruth and William Caldwell. Credit: Mike Holahan, Augusta University An enzyme under study to treat certain cancers is also showing promise in reducing the significant vision damage that can result from diabetes and premature birth, scientists report. Inflammation is considered a hallmark of cancer. It’s pervasive...