NIH/NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES IMAGE: A CAT CREDIT: NIAID An experimental approach to enhancing a standard cat allergy treatment made it more effective and faster acting, and the benefits persisted for a year after treatment ended, a study supported by the National Institutes of Health has found. The findings were published Monday...
Cleveland Clinic researchers identify diabetes drug metformin as potential atrial fibrillation treatment in collaborative research
CLEVELAND CLINIC October 11, 2022, CLEVELAND: Cleveland Clinic researchers have identified a common diabetes medication, metformin, as a possible treatment for atrial fibrillation. The study, published in Cell Reports Medicine, built on ongoing collaborative Cleveland Clinic research to support further investigation into metformin as a drug repurposing candidate. Researchers used advanced computation and genetic sequencing...
PC deficiency suppresses seipin: New insights into Berardinelli-Seip congenital lipodystrophy type 2
HIGHER EDUCATION PRESS IMAGE: THE ROLE OF PC, PUFAS AND SEIP-1 IN THE REGULATION OF EMBRYOGENESIS AND LIPID DROPLET HOMEOSTASIS (PC DEFICIENCY ENHANCES THE LIPID DROPLET PHENOTYPE OF SEIP-1 MUTANTS). CREDIT: JINGLIN ZHU, SIN MAN LAM, LEILEI YANG, JINGJING LIANG, MEI DING, GUANGHOU SHUI, XUN HUANG Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2), the most severe...
Exceptional Honeymoon Areas USA and the International Marital relationship Broker Regulations Act
Thousands of United States citizens use for-profit intercontinental marriage agents each year to discover a foreign spouse. These companies charge service fees to match American citizens with overseas nationals, facilitating partnerships and immigration. Nevertheless, the use of these brokers can place a woman living abroad in a harmful situation. The International Marital life Broker Control...
Age vs. genetics: Which is more important for determining how we age?
by Robert Sanders, University of California – Berkeley Age impacts the predictive power of eQTLs in many tissues. Credit: Nature Communications (2022). DOI: 10.1038/s41467-022-33509-0 Amid much speculation and research about how our genetics affect the way we age, a University of California, Berkeley, study now shows that individual differences in our DNA matter less as we get...
Individuals with inflammatory breast cancer at higher risk of cancer spread to the brain
by Wiley Credit: Unsplash/CC0 Public Domain New research indicates that among individuals with breast cancer, those with a rare subtype called inflammatory breast cancer face a higher risk that their cancer will spread, or metastasize, to the brain. The study is published online in the Cancer journal. Studies have demonstrated higher rates of brain metastases in patients...
Predicting risk of aneurysm rupture
AMERICAN INSTITUTE OF PHYSICS VIDEO: ANIMATION SHOWING AN ANEURYSM ARISING FROM A BLOOD VESSEL BIFURCATION, PROGRESSIVELY EXPANDING AND ENDING IN RUPTURE. CREDIT: SAJAN ABDUL SALAM, SUBASH M. NAIR, B. JAYANAND SUDHIR WASHINGTON, Oct. 11, 2022 – Cerebral aneurysms appear in 5% to 8% of the general population. The blood vessel rupture and resultant blood leakage...
A one-two punch: Low levels of a flavoring chemical and mild flu may damage lungs
by Susanne Pallo, University of Rochester Medical Center Credit: Unsplash/CC0 Public Domain We’ve known for two decades that chronic exposure to high levels of a flavoring chemical called diacetyl, which is found in many foods and beverages, can cause lung damage. Now, a University of Rochester Medical Center study suggests that even short-term exposures to...
Enzyme therapy shows promise for childhood dementia
by University of Edinburgh Graphical abstract. Credit: Journal of Clinical Investigation (2022). DOI: 10.1172/JCI163107 Studies into a rare nervous system disorder that causes dementia and early death in children have highlighted a possible treatment for the condition. Regular infusions of a key enzyme that is deficient in children with infantile Batten disease, also called CLN1 disease, led...
Researchers improve vehicle for delivering gene therapies to the central nervous system
by Brigham and Women’s Hospital Credit: Pixabay/CC0 Public Domain The blood-brain barrier (BBB) is an imposing foe for gene therapy. Formed of cells wedged tightly together, the BBB keeps toxins and pathogens that may be present in the blood from entering brain tissue, but it also keeps out potential treatment for diseases that affect the...