by United European Gastroenterology Credit: Unsplash/CC0 Public Domain Eating a Mediterranean diet rich in fiber, mono-unsaturated fatty acids and polyphenols, has been associated with improved immunotherapy response rates and progression-free survival in advanced melanoma patients, a new study presented today at UEG Week 2022 has found. Experts anticipate that the diet will play an important...
by Rod Chester, Queensland University of Technology Chemogenetic manipulation of 5-HTMRN>DG circuit modulates ethanol intake following long-term exposure. A–C mCherry-control, hM3Dq-excitatory, and hM4Di-inhibitory DREADDs were injected in pet1-5-HT MRN neurons and bilateral cannulae were implanted in the hippocampus, above the dentate gyrus (A). Expression of DREADD constructs in TPH2-immunoreactive MRN neurons was verified by immunohistochemistry (B,...
by Dipali Pathak, Baylor College of Medicine Credit: Unsplash/CC0 Public Domain As the weather cools down around the country, more people are taking the opportunity to enjoy outdoor activities. Whether it’s camping, hiking or hunting, an infectious diseases expert at Baylor College of Medicine gives tips on how to prevent tick bites this fall. “There...
by University of Rhode Island An adult deertick. Credit: University of Rhode Island TickEncounter If you’re a hiker or just love the outdoors, fall is probably your favorite season. Temperatures are cooler but still warm enough, days are still long, and for the most part, bugs are less of a pest. But as you get...
by Susanne Stöcker, Paul-Ehrlich-Institut – Bundesinstitut für Impfstoffe und biomedizinische Arzneimittel Credit: Pixabay/CC0 Public Domain In the search for effective and safe therapeutics for hyposensitization, colleagues at the Paul-Ehrlich-Institut and the Justus Liebig University in Giessen investigated the effect of the birch pollen allergen-containing fusion protein rFlaA:Betv1 on B cells (specific immune cells). rFlaA:Betv1 leads...
by University of Geneva Structure of the GNAO1 gene with the location of the three most frequent mutations. Credit: Larasati et al., Sci. Adv. 8, eabn9350 (2022) 21 October 2022 Pediatric encephalopathies of genetic origin cause severe motor and intellectual disabilities from birth. One of these diseases, first identified in 2013, is caused by mutations in the...
by Federico Graciano, Duke-NUS Medical School sVNT and pVNT assay. a, A heat map of sVNT GMT50 of 20 serum panels derived from convalescent, vaccinated, boosted and hybrid individuals for immunity against 20 sarbecoviruses using multiplex sVNT. b, Illustration of the clade-1b (SARS-CoV-2, RaTG13 and GX-P5L) and clade-2 (RmYN02 and SL-ZC45) RBDs used in rabbit...
Marcia Frellick October 07, 2022 As the United States enters a third fall with COVID-19, the virus for many is seemingly gone — or at least out of mind. But for those keeping watch, it is far from forgotten as deaths and infections continue to mount at a lower but steady pace. What does that mean for the...
By Michael Irving October 02, 2022 A new study could recontextualize metastasis in cancer Deposit photos Cancer’s ability to spread through the body is one of its most devastating tricks. Scientists at Cambridge have now identified a protein that plays a key role in metastasis, which not only hints at a new potential treatment but...
By Nick Lavars October 04, 2022 The Intracept procedure tackles lower back pain with heat via radio-frequency ablation Relievant Medsystems Persistent lower back pain is a debilitating problem for millions of people around the world, and it’s not something that is easily treated. A technology called Intracept is making waves in this space, carefully delivering...
