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The adult brain has the potential to partially recover from inherited blindness, study finds
by University of California, Irvine Graphical abstract. Credit: Current Biology (2022). DOI: 10.1016/j.cub.2022.09.005 A discovery about how some visually impaired adults could start to see offers a new vision of the brain’s possibilities. The finding that the adult brain has the potential to partially recover from inherited blindness comes from a collaboration between researchers in the University...
Ketamine and depression: A mechanism of the antidepressant revealed
by Institut du Cerveau (Paris Brain Institute) Mediation Results. Boxplots showing the IQRs for belief-updating biases (normalized by estimation error magnitude) and Montgomery-Åsberg Depression Rating Scale scores 24 h before and 1 wk after ketamine treatment. The black lines inside the boxplots show the median values, and the jitter elements left of each boxplot show...
Can you learn a language in your sleep? We found you may be able to pick up some words
by Matthieu Koroma, The Conversation For all sleep-learning’s promises, memorising words while awake was still five times more efficient. Credit: PaeGAG/Shutterstock From Aldous Huxley’s Brave New World to Dexter’s Laboratory cartoon series, sleep-learning has been a recurring theme in fiction. The idea that we can learn while asleep has fascinated many, but whether it is sheer fantasy or scientifically...
Human cocaine and heroin addiction tied to impairments in specific brain circuit initially implicated in animals
by The Mount Sinai Hospital Structural connections with the prefrontal cortex modeled from targeted nuclei in the subcortex (blue: habenula, yellow: anterior thalamus, red: ventral tegmental area) using diffusion MRI tractography. Microstructural properties of the habenula tract were uniquely reduced in individuals with cocaine or heroin use disorder. Results highlight the potential specificity of distinct...
Team develops tools and techniques to explore cancer signals at the subcellular level
by Jerry Grillo, Georgia Institute of Technology Graphical abstract. Credit: iScience (2022). DOI: 10.1016/j.isci.2022.104980 This year, about 240,000 people in the U.S. will discover they have lung cancer. Some 200,000 of them will be diagnosed with non-small-cell lung cancer, which is the second leading cause of death after cardiovascular disease. Georgia Tech researcher Ahmet Coskun is working...
Scientists discover protein partners that could heal heart muscle
by University of North Carolina Health Care Human fibroblasts reprogrammed into cardiomyocyte-like cells. Immunofluorescence shows different molecules: DNA (blue), cardiac Troponin T (orange) and αActinin (green). Credit: Qian Lab, UNC School of Medicine Scientists at the UNC School of Medicine have made a significant advance in the promising field of cellular reprogramming and organ regeneration,...
New bandage for foot ulcers could revolutionize diabetes treatment
by Queen’s University Belfast Credit: Drug Delivery and Translational Research (2022). DOI: 10.1007/s13346-022-01115-8 Researchers at Queen’s University Belfast have designed a new bandage treatment, known as a scaffold, to treat diabetic foot ulcers, which is cost-effective while improving patient outcomes. Produced by 3D bioprinting, the scaffolds slowly release antibiotics over a four-week period to effectively treat the...
Mapping human brain development
by Peter Rüegg, ETH Zurich Brain organoid from human stem cells under the fluorescence microscope: the protein GLI3 is stained purple and marks neuronal precursor cells in forebrain regions of the organoid. Neurons are stained green. Credit: F. Sanchís Calleja, A. Jain, P. Wahle / ETH Zurich The human brain is probably the most complex...
3D map reveals DNA organization within human retina cells
by National Eye Institute Credit: Unsplash/CC0 Public Domain National Eye Institute researchers mapped the organization of human retinal cell chromatin, the fibers that package 3 billion nucleotide-long DNA molecules into compact structures that fit into chromosomes within each cell’s nucleus. The resulting comprehensive gene regulatory network provides insights into regulation of gene expression in general,...