Neil Skolnik, MD September 27, 2022 I’m Dr Neil Skolnik, and today we are going to talk about the 2022 ACC Expert Consensus Decision Pathway on the Role of Nonstatin Therapies for LDL-Cholesterol Lowering in the Management of Atherosclerotic Cardiovascular Disease Risk: A Report of the American College of Cardiology Solution Set Oversight Committee, Journal of the American College...
Newly identified mechanism may explain why women are more vulnerable to Alzheimer’s disease
Reviewed by Emily Henderson, B.Sc. Oct 4 2022 Case Western Reserve University researchers have identified a mechanism in brain tissue that may explain why women are more vulnerable to Alzheimer’s disease-;a finding that they say could help lead to new medicines to treat the disease. Specifically, the researchers found that the female brain shows higher...
Which student-athletes can be safely released to an athletic trainer after concussion?
WOLTERS KLUWER HEALTH October 4, 2022 —When a high school or college student consults a physician about a sport-related concussion, their age, severity of symptoms, number of previous concussions, and family history of psychiatric disorders predict whether they can be released to supervision by an athletic trainer or will need additional medical care, according to an...
Study uncovers mechanisms of reactive oxygen species in stem cell function and inflammation prevention
by The Mount Sinai Hospital Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Credit: Wikipedia/CC BY-SA 3.0 Mount Sinai researchers have published one of the first studies to demonstrate the importance of reactive oxygen species in maintaining stem cell function and preventing inflammation during wound repair, which could...
Significant antiviral activity of bulevirtide for treatment of chronic hepatitis D infection
by Nicola Wittekindt, Deutsches Zentrum für Infektionsforschung Transmission electron micrograph image of hepatitis B virus particles. Credit: Betty Partin/CDC Between 10 and 20 million people worldwide are infected with hepatitis D virus (HDV). HDV infection is always associated with hepatitis B virus infection. So far there has been no satisfactory therapeutic option for this most...
Unique gene signature could help predict response to chemotherapy
by The Francis Crick Institute In vitro anticancer drug screen. a Volcano plots showing differences in IC50 values between RAS high and low CCLE cell lines. Drugs with enriched target annotations in the significant sensitive and resistant groups are highlighted (hypergeometric test) Drugs with an absolute log2 fold change >1 and fdr < 0.05 (linear model...
Which grains you eat can impact your risk of getting heart disease earlier
by American College of Cardiology Credit: Pixabay/CC0 Public Domain In one of the first studies to examine the relationship between different types of grain intake and premature coronary artery disease in the Middle East, researchers found a higher intake of refined grain was associated with an increased risk of premature coronary artery disease in an Iranian...
It’s flu vaccine time and seniors need revved-up shots
by LAURAN NEERGAARD A man receives a flu shot in Brattleboro, Vt., on Tuesday, Oct. 26, 2021. Doctors have a message for vaccine-weary Americans: Don’t skip your flu shot this fall 2022. And for the first time, seniors are urged to get a special extra-strength kind. Credit: Kristopher Radder/The Brattleboro Reformer via AP, File Doctors...
Malaria treatment is saving money while saving young lives
by University of Bergen a-c: Deterministic sensitivity analysis for Malawi; tornado diagram of community-delivered PDMC and facility-delivered PDMC versus standard of care (1a, 1b), and a comparison of both PDMC strategies (1c). Credit: eClinicalMedicine (2022). DOI: 10.1016/j.eclinm.2022.101669 Young children in sub-Saharan Africa often become severely anemic as consequence of a malaria infection. Treating them requires blood transfusions and...
Researchers develop non-invasive blood glucose monitoring process
by Kennesaw State University A new non-invasive blood glucose monitoring process is in development. Credit: Kennesaw State University As a child, Maria Valero witnessed her diabetic father prick his finger several times a day to draw blood and check his glucose levels using an electronic monitor. She was concerned about the invasive and painful process...