by University of Leeds Credit: Pixabay/CC0 Public Domain A rehabilitation program that helps people with long COVID reduce their symptoms and increase activity levels has shown “impressive” results, say scientists. It is based on a gradual or paced increase in a patient’s physical activity. Before the start of the program, the people taking part in...
Year: <span>2022</span>
Killing pancreatic cancer with T cells that supercharge themselves
by University of California, San Francisco Therapeutic T cells engineered with tumor-triggered IL-2 production infiltrate and clear immune-excluded tumors. (A) We hypothesized that cell autonomous cytokine delivery will allow for, safer, more effective delivery of key inflammatory cytokines like IL-2. Specifically, IL-2 induction circuits that utilize synNotch to bypass requirements for CAR/TCR activation and provide...
Loss of smell following COVID linked to a person’s immune reaction to the infection
by Bob Yirka, Medical Xpress Credit: Pixabay/CC0 Public Domain A team of researchers from Columbia University Irving Medical Center, the University of Pennsylvania, the National Institute of Alcohol Abuse and Alcoholism and the New York State Psychiatric Institute has found that a person’s loss of taste or smell due to a COVID-19 infection may be...
What premature ejaculation pills work?
There are many options for treating premature ejaculation, including prescription and over-the-counter (OTC) medication. Doctors may also recommend other treatment options for people with this condition. This article looks into the most common available medication for premature ejaculation (PE). It also explores the side effects of these medications, alternatives, and frequently asked questions. Please note that...
New PTSD treatment avenue? Blocking serotonin may reduce fear
Researchers are investigating whether blocking serotonin in the brain could help treat PTSD and anxiety disorders. Image credit: Producciones Visualix/Stocksy. People with post-traumatic stress disorder (PTSD) live with terrifying memories of traumatic events. Psychotherapy is the primary form of treatment offered to people with PTSD and other acute fears. Drugs may supplement such treatments. A new study...
New immune target to treat cardiovascular disease discovered
MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN For the longest time, clinicians have treated cardiovascular disease by focusing on diabetes and blood pressure control, reducing cholesterol using medications like aspirin and statins. Despite these measures, heart disease remains the number one cause of death in the United States, with many patients having heart attacks even after...
Activated vitamin D3 treatment may reduce the risk of arsenic-mediated skin cancer
SHIBAURA INSTITUTE OF TECHNOLOGY IMAGE: THE RISK OF CANCER ASSOCIATED WITH LONG-TERM EXPOSURE TO ARSENIC IN DRINKING WATER CAN BE MITIGATED THROUGH REGULAR TREATMENT WITH CALCITRIOL, AN ACTIVATED FORM OF VITAMIN D3. CREDIT: ICHIRO YAJIMA FROM SIT, JAPAN According to recent estimates, over 140 million people from 50 countries regularly get exposed to arsenic through...
Poor gut health may drive multiple sclerosis — better diet may ease it
RUTGERS UNIVERSITY Researchers from Rutgers Robert Wood Johnson Medical School’s Department of Neurology have traced a previously observed link between microscopic organisms in the digestive tract — collectively known as the gut microbiome — and multiple sclerosis (MS). Their study in genetically altered miceand people supports the belief that dietary adjustments such as increased fiber may slow...
New targets in the fight against pancreatic cancer
TOKYO MEDICAL AND DENTAL UNIVERSITY IMAGE: TOP, SETD1A, DIRECTLY RECRUITED TO THE RUVBL1 PROMOTER, ENHANCES RUVBL1 GENE EXPRESSION BY INCREASING H3K4ME3 LEVELS IN PANCREATIC CANCER CELLS. BOTTOM, HIGH CO-EXPRESSION OF SETD1A AND RUVBL1 CAN PREDICT WORSE PROGNOSIS THAN OTHERS. CREDIT: DEPARTMENT OF MOLECULAR ONCOLOGY, TMDU Researchers from Tokyo Medical and Dental University (TMDU) uncover an...
Researchers discover how to predict the efficacy of one of the most widely used drugs against breast cancer
by The Spanish National Cancer Research Centre Clinical trial tumor samples: the phosphoprofiles were independent of the study site and/or treatment arm. A Clinical trial treatment and sampling schedule. After randomization, patients were scheduled for a fresh tumor biopsy. Sixty-two and sixty-one patients allocated to the Experimental and Standard arms, respectively, consented to and underwent...