by Duke University Medical Center Credit: CC0 Public Domain A large study of military members led by researchers at Duke Health and the Durham VA identified four genes that are linked to an increased risk of suicidal thoughts and behaviors. While more work is needed to determine whether identification of the genetic markers might lead...
Year: <span>2022</span>
Gut microbes can boost the motivation to exercise, research finds
by Perelman School of Medicine at the University of Pennsylvania Illustration of bacteria in the human gut. Credit: Darryl Leja, National Human Genome Research Institute, National Institutes of Health Some species of gut-dwelling bacteria activate nerves in the gut to promote the desire to exercise, according to a study in mice that was led by...
Key to new lupus treatment could depend on protein in the blood
by SingHealth Serum CXCL5 levels are lower in Asian SLE patients and Faslpr mice, compared to healthy individuals and ICR mice controls, and negatively correlated with disease activity. (A) Serum CXCL5 levels in healthy individuals and Asian active SLE patients. (B)Correlation of serum CXCL5 and SLE disease activity index (SLEDAI) scores in Asian SLE patients. (C)...
Moderna says personalized mRNA cancer vaccine is effective for advanced melanoma
The company said that in a phase 2 clinical trial, the vaccine, when combined with immunotherapy drug Keytruda, reduced the risk of recurrence by 44%. A Moderna building in Cambridge, Mass., on May 18, 2020.Bill Sikes / AP fileLink copied Dec. 13, 2022, 10:13 AM MSTBy The Associated Press Moderna’s stock soared Tuesday after the Covid-19...
New study reveals hidden genetic anomaly behind common late-onset cerebellar ataxia
by University of Miami Leonard M. Miller School of Medicine A montage of three images of single striatal neurons transfected with a disease-associated version of huntingtin, the protein that causes Huntington’s disease. Nuclei of untransfected neurons are seen in the background (blue). The neuron in the center (yellow) contains an abnormal intracellular accumulation of huntingtin...
Class of diabetes drugs cuts dementia risk in older adults, research shows
by Erin Howe, University of Toronto Credit: CC0 Public Domain A class of medication for type 2 diabetes may help older people with the condition reduce their risk of dementia. The findings are contained in a new study by Walter Swardfager, an assistant professor of pharmacology and toxicology at the Temerty Faculty of Medicine and...
Olfactory viral inflammation associated with accelerated onset of Alzheimer’s disease
by CU Anschutz Medical Campus Immunohistochemistry of the Human OT and TempO-Seq Transcriptome Analysis of the OB and OT. (A-C) IHC of the human OT for 6 control and 6 FAD subjects. (A) PLP stain was used to delimitate the high and low myelinated regions in OT. The bar graph represents the mean surface of...
Brain stimulation found to improve reading ability in macular degeneration patients
by University of Waterloo The effect of tDCS on reading accuracy for Chinese characters (left plot) and English words (right plot). Sentences were presented one word or character at a time (stimulus inserts). Participants were tested before, during, 5 minutes after, and 30 minutes after application of tDCS. The Y-axis denotes the accuracy difference between...
Nearly half of deaths for 12 cancers in California are due to tobacco, higher than previously reported
by UC Davis Comprehensive Cancer Center Credit: CC0 Public Domain Despite California’s success in reducing tobacco use, a new study published today in JAMA Network Open demonstrates the continued and significant burden tobacco inflicts on people with cancer. The study was conducted by researchers at UC Davis Comprehensive Cancer Center who used data collected from the California...
New study shows the incidence of Parkinson’s disease in the US is 50% higher than previous estimates
by Parkinson’s Foundation Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: Wikipedia A new study reveals that the annual incidence of Parkinson’s disease (PD) among older adults is 50% higher than current estimates of 60,000 diagnoses annually. The peer-reviewed study, which measured new cases...