by Monash University Types of studies included in this review. RCT, randomized controlled trial. Credit: Epilepsia (2022). DOI: 10.1111/epi.17426 Older age is now the most common time to develop epilepsy in high-income settings, and an evidence review led by a Monash research team has highlighted that older adults are at risk of new-onset seizures due to age-related...
by Veterans Affairs Research Communications Credit: Pixabay/CC0 Public Domain A large Veterans Affairs (VA) clinical trial found that the blood pressure drug chlorthalidone (CTD) was not superior to hydrochlorothiazide (HCTZ) for the prevention of cardiovascular disease or non-cancer death. Both drugs are in a class of medications called thiazide diuretics, commonly known as water pills....
by University of Edinburgh Scanned images of whole kidneys comparing a healthy contralateral mouse kidney with a kidney after ischemia-reperfusion injury (IRI), with red staining indicative of fibrosis. Credit: Science Translational Medicine (2022). DOI: 10.1126/scitranslmed.abf5074 A serious condition that can cause the kidneys to suddenly stop working could be treated with existing medicines, a new study shows. In...
Miriam E. Tucker December 13, 2022 New more aggressive targets for blood pressure and lipids are among the changes to the annual American Diabetes Association (ADA) Standards of Care in Diabetes — 2023. The document, long considered the gold standard for care of the more than 100 million Americans living with diabetes and prediabetes, was published December 12 as a supplement in Diabetes...
by The Scripps Research Institute In postmenopausal women, depletion of estrogen causes excessive elevation of nitric oxide (NO) in the brain and thus generates S-nitrosylated complement factor C3 (SNO-C3). SNO-C3 triggers activated microglial cells, the innate immune cells in the brain, to phagocytose (or ‘eat’) neuronal synapses—the connections that mediate signaling between nerve cells in...
by Bob Yirka, Medical Xpress Credit: Pixabay/CC0 Public Domain A combined team of researchers from University Roma Tre and Nova Mentis Life Science Corp. has found that administering microdoses of psilocybin to rats with fragile X syndrome (FXS), an autism-like disease, improves some aspects of cognitive performance. In their paper published in the journal Psychopharmacology, the...
by Richard Harth, Arizona State University In a new study, Arizona State University researchers and their colleagues deeply explore changes in the gut microbiota following microbiota transfer therapy—a novel treatment for children with autism. Specifically, by using whole genome sequencing, they looked at alterations in bacterial species and genes involved with microbial metabolism. The researchers...
Radiofrequency ablation (RFA) is a minimally invasive treatment that can sometimes relieve chronic back pain. During the procedure, a doctor inserts a thin metal probe into the painful area. The probe emits radiofrequency energy that creates heat and destroys the nerve tissue that is causing pain. RFA is a relatively new procedure, though researchers have yet to...
The holidays can be magical times for children, but they can provoke stress, which can manifest in different ways than in adults. Schenike Massie-Lambert, program coordinator of the Rutgers Children’s Center for Resilience and Trauma Recovery at University Behavioral Health Care, discusses ways to keep children’s stress at bay during the holidays: Q Why might the holidays be...
Edelstein, a professor of French and, by courtesy, of history and political science, teaches in the Citizenship in the 21st Century class, part of Stanford University’s Civic, Liberal, and Global Education (COLLEGE) core curriculum. “To be successful citizens, we have to understand what is needed of us in our interactions with others and what are...
