by eLife A cell-by-cell tapestry of prostate cancer progression, which the authors created by applying a technique called UMAP to the entire dataset from their study. Credit: Germanos et al. (CC BY 4.0) Researchers have characterized prostate cancer cell dynamics at a single-cell resolution across the timespan of the disease—from its beginning to the point...
by Emerald Lake Safety Credit: Pixabay/CC0 Public Domain New research has confirmed a strong link between four genetic mutations and progressive multifocal leukoencephalopathy (PML), a rare but often fatal brain infection that can be triggered by dozens of FDA-approved drugs. The research, published in Frontiers in Neurology on December 14, will allow doctors to screen...
by Isabella Backman, Yale University Schematic illustration of how the α2A-AR agonist, guanfacine, and the anti-oxidant NAC, can have therapeutic effects in treating the symptoms of TBI and long-COVID by strengthening PFC neurotransmission and synaptic connections and reducing neuroinflammation. Layer III dlPFC microcircuits depend on NMDAR synapses on dendritic spines to produce the persistent neuronal...
Karen Weintraub USA TODAY The American Diabetes Association on Monday released new standards of care to reflect changes in technology, improved medications and a deeper understanding of the social factors that contribute to disease and diabetes control. The standards are updated annually, but this year includes almost 100 new or revised recommendations affecting all types...
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO Vitamin D plays an important role in the regulation of calcium and phosphorus absorption by the organism. It also helps keep the brain and immune system working. Researchers at the Federal University of São Carlos (UFSCar) in Brazil and University College London (UCL) in the...
UNIVERSITY OF CALIFORNIA – SAN DIEGO IMAGE: JAMES GILLRAY’S 1799 PAINTING ILLUSTRATES THE PAINFUL SYMPTOMS OF GOUT. CREDIT: WELLCOME LIBRARY, LONDON / HTTPS://CREATIVECOMMONS.ORG/LICENSES/BY/4.0/ Many Americans think of gout as a disease from a bygone era, akin to rickets or scurvy. The condition commonly afflicted the rich and royal, including American historical figures such as Benjamin Franklin...
UNIVERSITAT AUTONOMA DE BARCELONA In an article published in the journal Antioxidants, researchers from the Hospital de la Santa Creu i Sant Pau Research Institute (IIB Sant Pau) and the Universitat Autònoma de Barcelona demonstrate in animal models that water enriched with hydrogen molecules (H2) improves the symptomatology of neuropathic pain and related emotional disturbances....
by Northwestern University Credit: Unsplash/CC0 Public Domain The reason your three-pound brain doesn’t feel heavy is because it floats in a reservoir of cerebrospinal fluid (CSF), which flows in and around your brain and spinal cord. This liquid barrier between your brain and skull protects it from a hit to your head and bathes your...
by Adam Taylor, The Conversation Lab-grown organoids are made using stem cells. Credit: Microgen/ Shutterstock Human volunteers have received the first-ever transfusion of lab grown red blood cells in a groundbreaking scientific first. Volunteers received about 5ml-10ml of blood (around 1-2 teaspoons), which contained around 15 billion red blood cells. So far, volunteers who received the lab-grown blood...
by Jim Dryden, Washington University School of Medicine Older adults work with exercise trainers as part of a study to see whether exercise, mindfulness training, or both might improve cognitive performance in seniors. A new study did not show such improvements, though the researchers are continuing to explore whether there may be some cognitive effects...
