by Fred Hutchinson Cancer Center Cancer — Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0 A comprehensive analysis of more than 100,000 colorectal cancer (CRC) cases, led by researchers at the Fred Hutchinson Cancer Center in Seattle and 200 scientific collaborators worldwide, has identified more than 100 new genetic risk factors strongly linked with...
by Cedars-Sinai Medical Center A hairpin loop from a pre-mRNA. Highlighted are the nucleobases (green) and the ribose-phosphate backbone (blue). Note that this is a single strand of RNA that folds back upon itself. Credit: Vossman/ Wikipedia Investigators from the Smidt Heart Institute at Cedars-Sinai have identified how biological pacemaker cells—cells that control your heartbeat—can “fight...
by McMaster University Credit: Unsplash/CC0 Public Domain Long-term consumption of Allura Red food dye can be a potential trigger of inflammatory bowel diseases (IBDs), Crohn’s disease and ulcerative colitis, says McMaster University’s Waliul Khan. Researchers using experimental animal models of IBD found that continual exposure to Allura Red AC harms gut health and promotes inflammation. The...
by Bruno Geoffroy, University of Montreal Hospital Research Centre Neuroprotection mechanism of Lacticaseibacillus rhamnosus HA-114. ALS models have impaired carnitine shuttle, a mechanism to transport long chain fatty acids across the mitochondrial membrane for energy production via β-oxidation. Fatty acids, supplied by the probiotic bacteria, is believed to enter the mitochondria independently of the carnitine...
by German Cancer Research Center Negative regulation of bone formation by TAM receptor MERTK. a mRNA expression analysis of TAM receptor family Mertk, Tyro3, Axl, Gas6, and Pros1 in primary murine osteoblast cultures after 0, 7, 14, and 21 days (n = 3 biological replicates) (Mertk expression d0 vs. d7: p = 0.0002; d0 vs. d14: p = 0.0042; d0 vs. d21: p = 0.0172), (Tyro3 expression d0 vs. d7: p = 0.009; d0 vs. d14: p = 0.9604; d0 vs. d21: p = 0.2928), (Axl expression...
by British Medical Journal Credit: Pixabay/CC0 Public Domain Probiotic bacteria usually found in fermented foods, such as yogurt, sourdough bread, and miso soup, might help dispel the embarrassment of persistent bad breath (halitosis), finds a pooled data analysis of the available evidence, published in the open access journal BMJ Open. Lactobacillus salivarius, Lactobacillus reuteri, Streptococcus salivarius,...
by American Heart Association Credit: Unsplash/CC0 Public Domain Drinking two or more cups of coffee a day may double the risk of death from cardiovascular disease among people with severe high blood pressure (160/100 mm Hg or higher) but not people with high blood pressure not considered severe, according to research published today in the Journal...
by The Mount Sinai Hospital Individuals with coronary artery disease exist on a spectrum of disease, such as the amount of plaque build-up in the arteries of the heart; however, the disease is conventionally classified as broad categories of case (yes disease) or control (no disease), which may result in misdiagnosis. A digital marker for...
by Josef Blaszkiewicz, Medical University of South Carolina Expression of the MEF2C protein (green) in the nuclei of neuronal cells (stained with a neuronal marker protein in red) in the inner ear of a young adult mouse. Nuclei were stained with Dapi (blue). Image courtesy of Dr. Hainan Lang of the Medical University of South...
By MANSUR SHAHEEN DEPUTY HEALTH EDITOR FOR DAILYMAIL.COM PUBLISHED: 12:31 EST, 20 December 2022 | UPDATED: 13:44 EST, 20 December 2022 Two already-approved drugs may effectively treat the millions of Americans estimated to have long Covid. Guanfacine, an Attention Deficit/Hyperactive Disorder (ADHD) drug sold under the name Tenex, and N-acetylcysteine (NAC), a concussion drug that is branded Mucomyst...
