by Thomas Olafsen and Elin Doeland, University of Oslo The green colors show healthy mitochondria while the red ones are damaged mitochondria undergoing “clearance” by mitophagy. Credit: Xu-xu Zhuang One in six Norwegians over 80 is affected by Alzheimer’s disease. Numbers are even higher worldwide, and there is still no cure available. Researchers at the...
Year: <span>2022</span>
How common nutritional supplements may protect against traumatic brain injuries in sports
by Max Esterhuizen, Virginia Tech Credit: Pixabay/CC0 Public Domain The pouring rain and blustery wind gusts are brutal. The crowd is bone-chillingly cold, but they don’t care. Their favorite football team is on the field. Suddenly, a player turns up the tempo, plowing full force into the opponent. Cheers erupt in the stands. The player...
Booster dose of mRNA COVID-19 vaccine required for immune protection against Omicron variant of SARS-CoV-2, says study
by Massachusetts General Hospital Credit: Pixabay/CC0 Public Domain An additional “booster” dose of Moderna or Pfizer mRNA-based vaccine is needed to provide immunity against the Omicron variant of SARS-CoV-2, the virus that causes COVID-19, according to a study by researchers at the Ragon Institute of MGH, MIT, and Harvard. The results of this study, reported...
Running could improve brain function in people with Gulf War illness
by Jordan Newman, Texas A&M University Credit: Pixabay/CC0 Public Domain It has now been three decades since 700,000 American troops responded to the invasion of Kuwait in the first Gulf War, and more than a third of those troops still suffer from the same condition: Gulf War Illness (GWI). Previously labeled Gulf War syndrome, GWI...
Vaccine-like mRNA injection can be used to make CAR T cells in the body
by Perelman School of Medicine at the University of Pennsylvania Credit: CC0 Public Domain An experimental immunotherapy can temporarily reprogram patients’ immune cells to attack a specific target via only a single injection of messenger RNA (mRNA), similar to the mRNA-based COVID-19 vaccines, according to a new study from researchers in the Perelman School of...
Risk of overactive bladder associated with medications for dementia
by University of Houston Credit: Unsplash/CC0 Public Domain A study from the University of Houston College of Pharmacy, published in the Journal of the American Geriatrics Society, has evaluated the risk of overactive bladder (OAB) as a side effect of cholinesterase inhibitor (ChEI) drugs taken for dementia and Alzheimer’s disease. The research was based on the dissertation...
Anxiety and PTSD linked to increased myelin in brain’s gray matter
by University of California – Berkeley An fMRI scan of the brain of a military veteran with PTSD, showing gray matter regions with increased myelin. Credit: UCSF / Linda Chao A recent study links anxiety behavior in rats, as well as post traumatic stress disorder (PTSD) in military veterans, to increased myelin—a substance that expedites...
Innovative approach brings cell-reprogramming therapy for heart failure closer to reality
by Ana María Rodríguez, Ph.D., Baylor College of Medicine Using endothelial cell plasticity to improve fibroblast reprograming efficiency. Credit: The authors / Scott Holmes, C.M.I. Not too long ago, the idea of taking—for instance—a skin cell and transforming it into a muscle cell was unthinkable. About 10 years ago, however, revolutionary research showed that it...
Potential New Gene Editing Tools Uncovered
Few developments have rocked the biotechnology world or generated as much buzz as the discovery of CRISPR-Cas systems, a breakthrough in gene editing recognized in 2020 with a Nobel Prize. But these systems that naturally occur in bacteria are limited because they can make only small tweaks to genes. In recent years, scientists discovered a...
New resistance-busting antibiotic combination could extend the use of ‘last-resort’ antibiotics
Scientists have discovered a new potential treatment that has the ability to reverse antibiotic resistance in bacteria that cause conditions such as sepsis, pneumonia, and urinary tract infections. Carbapenems, such as meropenem, are a group of vital often ‘last-resort’ antibiotics used to treat serious, multi-drug resistant infections when other antibiotics, such as penicillin, have failed. But some...